Skip to main content
Gut logoLink to Gut
. 1993 Jul;34(7):865–868. doi: 10.1136/gut.34.7.865

Inflammatory bowel disease--a radical view.

N J Simmonds 1, D S Rampton 1
PMCID: PMC1374216  PMID: 8344570

Full text

PDF
865

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adeyemi E. O., Neumann S., Chadwick V. S., Hodgson H. J., Pepys M. B. Circulating human leucocyte elastase in patients with inflammatory bowel disease. Gut. 1985 Dec;26(12):1306–1311. doi: 10.1136/gut.26.12.1306. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Ahnfelt-Rønne I., Nielsen O. H., Christensen A., Langholz E., Binder V., Riis P. Clinical evidence supporting the radical scavenger mechanism of 5-aminosalicylic acid. Gastroenterology. 1990 May;98(5 Pt 1):1162–1169. doi: 10.1016/0016-5085(90)90329-y. [DOI] [PubMed] [Google Scholar]
  3. Baker S. S., Campbell C. L. Rat enterocyte injury by oxygen-dependent processes. Gastroenterology. 1991 Sep;101(3):716–720. doi: 10.1016/0016-5085(91)90530-x. [DOI] [PubMed] [Google Scholar]
  4. Bilotta J. J., Waye J. D. Hydrogen peroxide enteritis: the "snow white" sign. Gastrointest Endosc. 1989 Sep-Oct;35(5):428–430. doi: 10.1016/s0016-5107(89)72849-2. [DOI] [PubMed] [Google Scholar]
  5. Blake D. R., Allen R. E., Lunec J. Free radicals in biological systems--a review orientated to inflammatory processes. Br Med Bull. 1987 Apr;43(2):371–385. doi: 10.1093/oxfordjournals.bmb.a072188. [DOI] [PubMed] [Google Scholar]
  6. Christensen L. A., Fallingborg J., Abildgaard K., Jacobsen B. A., Sanchez G., Hansen S. H., Bondesen S., Hvidberg E. F., Rasmussen S. N. Topical and systemic availability of 5-aminosalicylate: comparisons of three controlled release preparations in man. Aliment Pharmacol Ther. 1990 Oct;4(5):523–533. doi: 10.1111/j.1365-2036.1990.tb00499.x. [DOI] [PubMed] [Google Scholar]
  7. Cross C. E., Halliwell B., Borish E. T., Pryor W. A., Ames B. N., Saul R. L., McCord J. M., Harman D. Oxygen radicals and human disease. Ann Intern Med. 1987 Oct;107(4):526–545. doi: 10.7326/0003-4819-107-4-526. [DOI] [PubMed] [Google Scholar]
  8. Dallegri F., Ottonello L., Ballestrero A., Bogliolo F., Ferrando F., Patrone F. Cytoprotection against neutrophil derived hypochlorous acid: a potential mechanism for the therapeutic action of 5-aminosalicylic acid in ulcerative colitis. Gut. 1990 Feb;31(2):184–186. doi: 10.1136/gut.31.2.184. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Dull B. J., Salata K., Van Langenhove A., Goldman P. 5-Aminosalicylate: oxidation by activated leukocytes and protection of cultured cells from oxidative damage. Biochem Pharmacol. 1987 Aug 1;36(15):2467–2472. doi: 10.1016/0006-2952(87)90518-1. [DOI] [PubMed] [Google Scholar]
  10. Emerit J., Pelletier S., Tosoni-Verlignue D., Mollet M. Phase II trial of copper zinc superoxide dismutase (CuZnSOD) in treatment of Crohn's disease. Free Radic Biol Med. 1989;7(2):145–149. doi: 10.1016/0891-5849(89)90005-1. [DOI] [PubMed] [Google Scholar]
  11. Friedl H. P., Till G. O., Ryan U. S., Ward P. A. Mediator-induced activation of xanthine oxidase in endothelial cells. FASEB J. 1989 Nov;3(13):2512–2518. doi: 10.1096/fasebj.3.13.2806779. [DOI] [PubMed] [Google Scholar]
  12. Grisham M. B., Granger D. N. Neutrophil-mediated mucosal injury. Role of reactive oxygen metabolites. Dig Dis Sci. 1988 Mar;33(3 Suppl):6S–15S. doi: 10.1007/BF01538126. [DOI] [PubMed] [Google Scholar]
  13. Grisham M. B., Volkmer C., Tso P., Yamada T. Metabolism of trinitrobenzene sulfonic acid by the rat colon produces reactive oxygen species. Gastroenterology. 1991 Aug;101(2):540–547. doi: 10.1016/0016-5085(91)90036-k. [DOI] [PubMed] [Google Scholar]
  14. Halliwell B., Aruoma O. I. DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems. FEBS Lett. 1991 Apr 9;281(1-2):9–19. doi: 10.1016/0014-5793(91)80347-6. [DOI] [PubMed] [Google Scholar]
  15. Hawkey C. J., Rampton D. S. Prostaglandins and the gastrointestinal mucosa: are they important in its function, disease, or treatment? Gastroenterology. 1985 Nov;89(5):1162–1188. doi: 10.1016/0016-5085(85)90225-2. [DOI] [PubMed] [Google Scholar]
  16. Ireland A., Jewell D. P. Mechanism of action of 5-aminosalicylic acid and its derivatives. Clin Sci (Lond) 1990 Feb;78(2):119–125. doi: 10.1042/cs0780119. [DOI] [PubMed] [Google Scholar]
  17. Keshavarzian A., Doria M. I., Sedghi S., Kanofsky J. R., Hecht D., Holmes E. W., Ibrahim C., List T., Urban G., Gaginella T. Mitomycin C-induced colitis in rats: a new animal model of acute colonic inflammation implicating reactive oxygen species. J Lab Clin Med. 1992 Nov;120(5):778–791. [PubMed] [Google Scholar]
  18. Keshavarzian A., Morgan G., Sedghi S., Gordon J. H., Doria M. Role of reactive oxygen metabolites in experimental colitis. Gut. 1990 Jul;31(7):786–790. doi: 10.1136/gut.31.7.786. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Keshavarzian A., Sedghi S., Kanofsky J., List T., Robinson C., Ibrahim C., Winship D. Excessive production of reactive oxygen metabolites by inflamed colon: analysis by chemiluminescence probe. Gastroenterology. 1992 Jul;103(1):177–185. doi: 10.1016/0016-5085(92)91111-g. [DOI] [PubMed] [Google Scholar]
  20. Levin K. E., Pemberton J. H., Phillips S. F., Zinsmeister A. R., Pezim M. E. Role of oxygen free radicals in the etiology of pouchitis. Dis Colon Rectum. 1992 May;35(5):452–456. doi: 10.1007/BF02049401. [DOI] [PubMed] [Google Scholar]
  21. Ma T. Y., Hollander D., Freeman D., Nguyen T., Krugliak P. Oxygen free radical injury of IEC-18 small intestinal epithelial cell monolayers. Gastroenterology. 1991 Jun;100(6):1533–1543. doi: 10.1016/0016-5085(91)90650-a. [DOI] [PubMed] [Google Scholar]
  22. Markowitz M. M., Rozen P., Pero R. W., Tobi M., Miller D. G. Hydrogen peroxide induced adenosine diphosphate ribosyl transferase (ADPRT) response in patients with inflammatory bowel disease. Gut. 1988 Dec;29(12):1680–1686. doi: 10.1136/gut.29.12.1680. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Mulder T. P., Verspaget H. W., Janssens A. R., de Bruin P. A., Peña A. S., Lamers C. B. Decrease in two intestinal copper/zinc containing proteins with antioxidant function in inflammatory bowel disease. Gut. 1991 Oct;32(10):1146–1150. doi: 10.1136/gut.32.10.1146. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Parks D. A., Bulkley G. B., Granger D. N. Role of oxygen-derived free radicals in digestive tract diseases. Surgery. 1983 Sep;94(3):415–422. [PubMed] [Google Scholar]
  25. Pero R. W., Roush G. C., Markowitz M. M., Miller D. G. Oxidative stress, DNA repair, and cancer susceptibility. Cancer Detect Prev. 1990;14(5):555–561. [PubMed] [Google Scholar]
  26. Salim A. S. Role of oxygen-derived free radical scavengers in the management of recurrent attacks of ulcerative colitis: a new approach. J Lab Clin Med. 1992 Jun;119(6):710–717. [PubMed] [Google Scholar]
  27. Schreck R., Rieber P., Baeuerle P. A. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J. 1991 Aug;10(8):2247–2258. doi: 10.1002/j.1460-2075.1991.tb07761.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Simmonds N. J., Allen R. E., Stevens T. R., Van Someren R. N., Blake D. R., Rampton D. S. Chemiluminescence assay of mucosal reactive oxygen metabolites in inflammatory bowel disease. Gastroenterology. 1992 Jul;103(1):186–196. doi: 10.1016/0016-5085(92)91112-h. [DOI] [PubMed] [Google Scholar]
  29. Sturzaker H. G., Hawley P. R. Collagenase activity in rectal and colonic biopsies. Proc R Soc Med. 1975 Jan;68(1):33–33. [PMC free article] [PubMed] [Google Scholar]
  30. Tamai H., Levin S., Gaginella T. S. Induction of colitis in rats by 2-2'-azobis(2-amidinopropane) dihydrochloride. Inflammation. 1992 Feb;16(1):69–81. doi: 10.1007/BF00917516. [DOI] [PubMed] [Google Scholar]
  31. Verspaget H. W., Peña A. S., Weterman I. T., Lamers C. B. Diminished neutrophil function in Crohn's disease and ulcerative colitis identified by decreased oxidative metabolism and low superoxide dismutase content. Gut. 1988 Feb;29(2):223–228. doi: 10.1136/gut.29.2.223. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Wakefield A. J., Sawyerr A. M., Dhillon A. P., Pittilo R. M., Rowles P. M., Lewis A. A., Pounder R. E. Pathogenesis of Crohn's disease: multifocal gastrointestinal infarction. Lancet. 1989 Nov 4;2(8671):1057–1062. doi: 10.1016/s0140-6736(89)91078-7. [DOI] [PubMed] [Google Scholar]
  33. Weiss S. J. Tissue destruction by neutrophils. N Engl J Med. 1989 Feb 9;320(6):365–376. doi: 10.1056/NEJM198902093200606. [DOI] [PubMed] [Google Scholar]
  34. Weitzman S. A., Gordon L. I. Inflammation and cancer: role of phagocyte-generated oxidants in carcinogenesis. Blood. 1990 Aug 15;76(4):655–663. [PubMed] [Google Scholar]
  35. Williams J. G. Phagocytes, toxic oxygen metabolites and inflammatory bowel disease: implications for treatment. Ann R Coll Surg Engl. 1990 Jul;72(4):253–262. [PMC free article] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES