Abstract
Three different experiments were carried out on growing male Sprague-Dawley rats. In the first experiment, dietary nitrogen was given in casein at four different protein values ranging from 5 to 16%. Rats were fed ad libitum for 21 days. In the second experiment, which lasted 17 days, animals were given three diets that differed in the molecular form of the nitrogen supply - that is, proteins or peptides. The protein value (N x 6.25) was 10% in each diet. In the third experiment, malnourished rats were refed diets with a protein value of 15% (N x 6.25) for eight days. The dietary nitrogen was either in the form of protein, peptide, or amino acid. Body weight was recorded daily. At the end of each experiment the intestinal villus height was measured by light microscopy. Data were statistically analysed by Exner's coefficient. The results assessed the validity of the correlation between villus height and gain in body weight.
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Selected References
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- Aldewachi H. S., Wright N. A., Appleton D. R., Watson A. J. The effect of starvation and refeeding on cell population kinetics in the rat small bowel mucosa. J Anat. 1975 Feb;119(Pt 1):105–121. [PMC free article] [PubMed] [Google Scholar]
- Challacombe D. N., McDonald D. T., Wheeler E. E. A quantitative assessment of jejunal villous damage in coeliac disease, using the mucosal index. Hepatogastroenterology. 1983 Jun;30(3):113–115. [PubMed] [Google Scholar]
- DEO M. G., RAMALINGASWAMI V. REACTION OF THE SMALL INTESTINE TO INDUCED PROTEIN MALNUTRITION IN RHESUS MONKEYS. A STUDY OF CELL POPULATION KINETICS IN THE JEJUNUM. Gastroenterology. 1965 Aug;49:150–157. [PubMed] [Google Scholar]
- Davidson A. G., Bridges M. A. Coeliac disease: a critical review of aetiology and pathogenesis. Clin Chim Acta. 1987 Feb 27;163(1):1–40. doi: 10.1016/0009-8981(87)90031-3. [DOI] [PubMed] [Google Scholar]
- Dowling R. H. Small bowel adaptation and its regulation. Scand J Gastroenterol Suppl. 1982;74:53–74. [PubMed] [Google Scholar]
- Hagemann R. F., Stragand J. J. Fasting and refeeding: cell kinetic response of jejunum, ileum and colon. Cell Tissue Kinet. 1977 Jan;10(1):3–14. doi: 10.1111/j.1365-2184.1977.tb00278.x. [DOI] [PubMed] [Google Scholar]
- Howdle P. D., Corazza G. R., Bullen A. W., Losowsky M. S. Gluten sensitivity of small intestinal mucosa in vitro: quantitative assessment of histologic change. Gastroenterology. 1981 Mar;80(3):442–450. [PubMed] [Google Scholar]
- King I. S., Paterson J. Y., Peacock M. A., Smith M. W., Syme G. Effect of diet upon enterocyte differentiation in the rat jejunum. J Physiol. 1983 Nov;344:465–481. doi: 10.1113/jphysiol.1983.sp014952. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Koga A., Kimura S. Influence of restricted diet on the cell cycle in the crypt of mouse small intestine. J Nutr Sci Vitaminol (Tokyo) 1980;26(1):33–38. doi: 10.3177/jnsv.26.33. [DOI] [PubMed] [Google Scholar]
- Misch D. W., Giebel P. E., Faust R. G. Intestinal microvilli: responses to feeding and fasting. Eur J Cell Biol. 1980 Aug;21(3):269–279. [PubMed] [Google Scholar]
- Rouanet J. M., Zambonino Infante J. L., Caporiccio B., Pejoan C. Nutritional value and intestinal effects of dipeptides and tripeptides. Comparison with their issuing bovine plasma protein in rats. Ann Nutr Metab. 1990;34(3):175–182. doi: 10.1159/000177584. [DOI] [PubMed] [Google Scholar]
- Sjölander A., Magnusson K. E., Latkovic S. Morphological changes of rat small intestine after short-time exposure to concanavalin A or wheat germ agglutinin. Cell Struct Funct. 1986 Sep;11(3):285–293. doi: 10.1247/csf.11.285. [DOI] [PubMed] [Google Scholar]
- Syme G., Smith M. W. Intestinal adaptation of protein deficiency. Cell Biol Int Rep. 1982 Jun;6(6):573–578. doi: 10.1016/0309-1651(82)90181-3. [DOI] [PubMed] [Google Scholar]
- Trahair J. F., Robinson P. M. An integrated model for intestinal development in the fetal sheep. Reprod Nutr Dev. 1987;27(4):849–857. doi: 10.1051/rnd:19870611. [DOI] [PubMed] [Google Scholar]
- Williamson R. C. Intestinal adaptation (first of two parts). Structural, functional and cytokinetic changes. N Engl J Med. 1978 Jun 22;298(25):1393–1402. doi: 10.1056/NEJM197806222982505. [DOI] [PubMed] [Google Scholar]
