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. 1994 Mar;35(3):309–312. doi: 10.1136/gut.35.3.309

Prevalence of peptic ulcer in Helicobacter pylori positive blood donors.

D Vaira 1, M Miglioli 1, P Mulè 1, J Holton 1, M Menegatti 1, M Vergura 1, G Biasco 1, R Conte 1, R P Logan 1, L Barbara 1
PMCID: PMC1374580  PMID: 8150337

Abstract

This study aimed to determine the importance of raised antibodies to Helicobacter pylori in an asymptomatic population. A total of 128 asymptomatic blood donors who were seropositive for H pylori and consented to endoscopy were investigated. These subjects were from a population of 1010 blood donors screened for antibodies to H pylori. A questionnaire was completed to determine if any subjects had complained of symptoms, and they subsequently had endoscopy. Altogether 121 of 128 were positive for H pylori by histology and urease test and/or culture and all 121 had chronic active gastritis on histology. Twenty five of these subjects had peptic ulcer (20 duodenal, five gastric), a further 21 had erosive duodenitis, and two were found to have gastric cancer. H pylori associated peptic ulcer disease and duodenitis occur more frequently than previously recognised and this suggests that H pylori infection, even if asymptomatic, is of far greater clinical relevance than originally thought.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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