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American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1998 Feb;62(2):215–220. doi: 10.1086/301736

Variability in immune response to pathogens: using measles vaccine to probe immunogenetic determinants of response.

G A Poland 1
PMCID: PMC1376909  PMID: 9463343

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Selected References

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  1. Androlewicz M. J., Anderson K. S., Cresswell P. Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner. Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):9130–9134. doi: 10.1073/pnas.90.19.9130. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Aoki Y., Isselbacher K. J., Pillai S. Polymorphisms involving the transmembrane domains of human TAP2. Immunogenetics. 1993;38(5):382–382. doi: 10.1007/BF00210485. [DOI] [PubMed] [Google Scholar]
  3. Barron K. S., Reveille J. D., Carrington M., Mann D. L., Robinson M. A. Susceptibility to Reiter's syndrome is associated with alleles of TAP genes. Arthritis Rheum. 1995 May;38(5):684–689. doi: 10.1002/art.1780380517. [DOI] [PubMed] [Google Scholar]
  4. Black F. L., Pinheiro F., Hierholzer W. J., Lee R. V. Epidemiology of infectious disease: the example of measles. Ciba Found Symp. 1977;(49):115–130. doi: 10.1002/9780470715406.ch7. [DOI] [PubMed] [Google Scholar]
  5. Black F. L., Salzano F. M. Evidence for heterosis in the HLA system. Am J Hum Genet. 1981 Nov;33(6):894–899. [PMC free article] [PubMed] [Google Scholar]
  6. Bodmer J. World distribution of HLA alleles and implications for disease. Ciba Found Symp. 1996;197:233–258. doi: 10.1002/9780470514887.ch13. [DOI] [PubMed] [Google Scholar]
  7. Chen R. T., Markowitz L. E., Albrecht P., Stewart J. A., Mofenson L. M., Preblud S. R., Orenstein W. A. Measles antibody: reevaluation of protective titers. J Infect Dis. 1990 Nov;162(5):1036–1042. doi: 10.1093/infdis/162.5.1036. [DOI] [PubMed] [Google Scholar]
  8. Deseda-Tous J., Cherry J. D., Spencer M. J., Welliver R. C., Boyer K. M., Dudley J. P., Zahradnik J. M., Krause P. J., Walbergh E. W. Measles revaccination. Persistence and degree of antibody titer by type of immune response. Am J Dis Child. 1978 Mar;132(3):287–290. doi: 10.1001/archpedi.1978.02120280071015. [DOI] [PubMed] [Google Scholar]
  9. Detels R., Mann D., Carrington M., Hennessey K., Wu Z., Hirji K. F., Wiley D., Visscher B. R., Giorgi J. V. Persistently seronegative men from whom HIV-1 has been isolated are genetically and immunologically distinct. Immunol Lett. 1996 Jun;51(1-2):29–33. doi: 10.1016/0165-2478(96)02551-5. [DOI] [PubMed] [Google Scholar]
  10. Deverson E. V., Gow I. R., Coadwell W. J., Monaco J. J., Butcher G. W., Howard J. C. MHC class II region encoding proteins related to the multidrug resistance family of transmembrane transporters. Nature. 1990 Dec 20;348(6303):738–741. doi: 10.1038/348738a0. [DOI] [PubMed] [Google Scholar]
  11. Hayney M. S., Dimanlig P., Lipsky J. J., Poland G. A. Utility of a "swish and spit" technique for the collection of buccal cells for TAP haplotype determination. Mayo Clin Proc. 1995 Oct;70(10):951–954. doi: 10.4065/70.10.951. [DOI] [PubMed] [Google Scholar]
  12. Hayney M. S., Poland G. A., Dimanlig P., Schaid D. J., Jacobson R. M., Lipsky J. J. Polymorphisms of the TAP2 gene may influence antibody response to live measles vaccine virus. Vaccine. 1997 Jan;15(1):3–6. doi: 10.1016/s0264-410x(96)00133-8. [DOI] [PubMed] [Google Scholar]
  13. Hayney M. S., Poland G. A., Jacobson R. M., Schaid D. J., Lipsky J. J. The influence of the HLA-DRB1*13 allele on measles vaccine response. J Investig Med. 1996 Jun;44(5):261–263. [PubMed] [Google Scholar]
  14. Heemels M. T., Ploegh H. L. Substrate specificity of allelic variants of the TAP peptide transporter. Immunity. 1994 Dec;1(9):775–784. doi: 10.1016/s1074-7613(94)80019-7. [DOI] [PubMed] [Google Scholar]
  15. Hill A., Ploegh H. Getting the inside out: the transporter associated with antigen processing (TAP) and the presentation of viral antigen. Proc Natl Acad Sci U S A. 1995 Jan 17;92(2):341–343. doi: 10.1073/pnas.92.2.341. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Jacobson S., Richert J. R., Biddison W. E., Satinsky A., Hartzman R. J., McFarland H. F. Measles virus-specific T4+ human cytotoxic T cell clones are restricted by class II HLA antigens. J Immunol. 1984 Aug;133(2):754–757. [PubMed] [Google Scholar]
  17. Jacobson S., Sekaly R. P., Bellini W. J., Johnson C. L., McFarland H. F., Long E. O. Recognition of intracellular measles virus antigens by HLA class II restricted measles virus-specific cytotoxic T lymphocytes. Ann N Y Acad Sci. 1988;540:352–353. doi: 10.1111/j.1749-6632.1988.tb27096.x. [DOI] [PubMed] [Google Scholar]
  18. Jacobson S., Sekaly R. P., Jacobson C. L., McFarland H. F., Long E. O. HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells. J Virol. 1989 Apr;63(4):1756–1762. doi: 10.1128/jvi.63.4.1756-1762.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Kaslow R. A., Carrington M., Apple R., Park L., Muñoz A., Saah A. J., Goedert J. J., Winkler C., O'Brien S. J., Rinaldo C. Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection. Nat Med. 1996 Apr;2(4):405–411. doi: 10.1038/nm0496-405. [DOI] [PubMed] [Google Scholar]
  20. Leopardi R., Ilonen J., Mattila L., Salmi A. A. Effect of measles virus infection on MHC class II expression and antigen presentation in human monocytes. Cell Immunol. 1993 Apr 1;147(2):388–396. doi: 10.1006/cimm.1993.1078. [DOI] [PubMed] [Google Scholar]
  21. Long E. O., Jacobson S. Pathways of viral antigen processing and presentation to CTL: defined by the mode of virus entry? Immunol Today. 1989 Feb;10(2):45–48. doi: 10.1016/0167-5699(89)90303-4. [DOI] [PubMed] [Google Scholar]
  22. Malnati M. S., Marti M., LaVaute T., Jaraquemada D., Biddison W., DeMars R., Long E. O. Processing pathways for presentation of cytosolic antigen to MHC class II-restricted T cells. Nature. 1992 Jun 25;357(6380):702–704. doi: 10.1038/357702a0. [DOI] [PubMed] [Google Scholar]
  23. Mathias R. G., Meekison W. G., Arcand T. A., Schechter M. T. The role of secondary vaccine failures in measles outbreaks. Am J Public Health. 1989 Apr;79(4):475–478. doi: 10.2105/ajph.79.4.475. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Momburg F., Roelse J., Howard J. C., Butcher G. W., Hämmerling G. J., Neefjes J. J. Selectivity of MHC-encoded peptide transporters from human, mouse and rat. Nature. 1994 Feb 17;367(6464):648–651. doi: 10.1038/367648a0. [DOI] [PubMed] [Google Scholar]
  25. Neefjes J. J., Momburg F., Hämmerling G. J. Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter. Science. 1993 Aug 6;261(5122):769–771. doi: 10.1126/science.8342042. [DOI] [PubMed] [Google Scholar]
  26. Neefjes J., Gottfried E., Roelse J., Grommé M., Obst R., Hämmerling G. J., Momburg F. Analysis of the fine specificity of rat, mouse and human TAP peptide transporters. Eur J Immunol. 1995 Apr;25(4):1133–1136. doi: 10.1002/eji.1830250444. [DOI] [PubMed] [Google Scholar]
  27. Nuchtern J. G., Biddison W. E., Klausner R. D. Class II MHC molecules can use the endogenous pathway of antigen presentation. Nature. 1990 Jan 4;343(6253):74–76. doi: 10.1038/343074a0. [DOI] [PubMed] [Google Scholar]
  28. Powis S. H., Tonks S., Mockridge I., Kelly A. P., Bodmer J. G., Trowsdale J. Alleles and haplotypes of the MHC-encoded ABC transporters TAP1 and TAP2. Immunogenetics. 1993;37(5):373–380. doi: 10.1007/BF00216802. [DOI] [PubMed] [Google Scholar]
  29. Quadri S. A., Ye M., Singal D. P. Polymorphism in transporter associated proteins within an antigen processing (TAP2) gene located in the HLA class II region. Transplant Proc. 1995 Feb;27(1):680–681. [PubMed] [Google Scholar]
  30. Savage D. A., Ng S. C., Howe H. S., Ngai J. L., Darke C., Hui K. M. HLA and TAP associations in Chinese systemic lupus erythematosus patients. Tissue Antigens. 1995 Sep;46(3 ):213–216. doi: 10.1111/j.1399-0039.1995.tb03123.x. [DOI] [PubMed] [Google Scholar]
  31. Shepherd J. C., Schumacher T. N., Ashton-Rickardt P. G., Imaeda S., Ploegh H. L., Janeway C. A., Jr, Tonegawa S. TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective. Cell. 1993 Aug 13;74(3):577–584. doi: 10.1016/0092-8674(93)80058-m. [DOI] [PubMed] [Google Scholar]
  32. Singh N., Agrawal S., Rastogi A. K. Infectious diseases and immunity: special reference to major histocompatibility complex. Emerg Infect Dis. 1997 Jan-Mar;3(1):41–49. doi: 10.3201/eid0301.970105. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Spies T., Bresnahan M., Bahram S., Arnold D., Blanck G., Mellins E., Pious D., DeMars R. A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway. Nature. 1990 Dec 20;348(6303):744–747. doi: 10.1038/348744a0. [DOI] [PubMed] [Google Scholar]
  34. Szafer F., Oksenberg J. R., Steinman L. New allelic polymorphisms in TAP genes. Immunogenetics. 1994;39(5):374–374. doi: 10.1007/BF00189240. [DOI] [PubMed] [Google Scholar]
  35. Townsend A., Trowsdale J. The transporters associated with antigen presentation. Semin Cell Biol. 1993 Feb;4(1):53–61. doi: 10.1006/scel.1993.1007. [DOI] [PubMed] [Google Scholar]
  36. Trowsdale J., Hanson I., Mockridge I., Beck S., Townsend A., Kelly A. Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters. Nature. 1990 Dec 20;348(6303):741–744. doi: 10.1038/348741a0. [DOI] [PubMed] [Google Scholar]
  37. Weiss S., Bogen B. MHC class II-restricted presentation of intracellular antigen. Cell. 1991 Feb 22;64(4):767–776. doi: 10.1016/0092-8674(91)90506-t. [DOI] [PubMed] [Google Scholar]

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