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. 1989 Jan;30(1):19–25. doi: 10.1136/gut.30.1.19

Constancy of glucose and starch fermentations by two different human faecal microbial communities.

G A Weaver 1, J A Krause 1, T L Miller 1, M J Wolin 1
PMCID: PMC1378224  PMID: 2920921

Abstract

The fermentation of glucose and corn starch by faecal suspensions from two subjects was examined over a three and a half year period. The substrate specificity and products of the faecal fermentations of each subject were relatively stable during this period and were significantly different between subjects. The major soluble end products of fermentation of glucose or starch were acetate, propionate, and butyrate. Hydrogen temporarily accumulated and was subsequently used in fermentations by both subjects. Hydrogen was used without methane production in fermentations of subject 1, but was used for methane formation in fermentations of subject 2. Although the rates of glucose fermentation were similar between both subjects; subject 1 produced a significantly greater molar ratio of propionate than did subject 2. The rate of fermentation of starch by faecal suspensions from subject 1 was faster than that of subject 2. The molar ratio of butyrate was greater for starch fermentations by subject 2, while the molar ratio of propionate was greater with subject 1. Significant differences were found between subjects in molar ratios and concentration of acetate and propionate and concentrations of butyrate in faeces.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson I. H., Levine A. S., Levitt M. D. Incomplete absorption of the carbohydrate in all-purpose wheat flour. N Engl J Med. 1981 Apr 9;304(15):891–892. doi: 10.1056/NEJM198104093041507. [DOI] [PubMed] [Google Scholar]
  2. Bond J. H., Jr, Engel R. R., Levitt M. D. Factors influencing pulmonary methane excretion in man. An indirect method of studying the in situ metabolism of the methane-producing colonic bacteria. J Exp Med. 1971 Mar 1;133(3):572–588. doi: 10.1084/jem.133.3.572. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bond J. H., Levitt M. D. Quantitative measurement of lactose absorption. Gastroenterology. 1976 Jun;70(6):1058–1062. [PubMed] [Google Scholar]
  4. Ehle F. R., Robertson J. B., Van Soest P. J. Influence of dietary fibers on fermentation in the human large intestine. J Nutr. 1982 Jan;112(1):158–166. doi: 10.1093/jn/112.1.158. [DOI] [PubMed] [Google Scholar]
  5. Englyst H. N., Cummings J. H. Digestion of polysaccharides of potato in the small intestine of man. Am J Clin Nutr. 1987 Feb;45(2):423–431. doi: 10.1093/ajcn/45.2.423. [DOI] [PubMed] [Google Scholar]
  6. Englyst H. N., Cummings J. H. Digestion of the polysaccharides of some cereal foods in the human small intestine. Am J Clin Nutr. 1985 Nov;42(5):778–787. doi: 10.1093/ajcn/42.5.778. [DOI] [PubMed] [Google Scholar]
  7. Miller T. L., Wolin M. J. A serum bottle modification of the Hungate technique for cultivating obligate anaerobes. Appl Microbiol. 1974 May;27(5):985–987. doi: 10.1128/am.27.5.985-987.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Miller T. L., Wolin M. J. Stability of Methanobrevibacter smithii populations in the microbial flora excreted from the human large bowel. Appl Environ Microbiol. 1983 Jan;45(1):317–318. doi: 10.1128/aem.45.1.317-318.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Stephen A. M., Haddad A. C., Phillips S. F. Passage of carbohydrate into the colon. Direct measurements in humans. Gastroenterology. 1983 Sep;85(3):589–595. [PubMed] [Google Scholar]
  10. Thornton J. R., Dryden A., Kelleher J., Losowsky M. S. Super-efficient starch absorption. A risk factor for colonic neoplasia? Dig Dis Sci. 1987 Oct;32(10):1088–1091. doi: 10.1007/BF01300193. [DOI] [PubMed] [Google Scholar]
  11. Weaver G. A., Krause J. A., Miller T. L., Wolin M. J. Incidence of methanogenic bacteria in a sigmoidoscopy population: an association of methanogenic bacteria and diverticulosis. Gut. 1986 Jun;27(6):698–704. doi: 10.1136/gut.27.6.698. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Wolin M. J. Fermentation in the rumen and human large intestine. Science. 1981 Sep 25;213(4515):1463–1468. doi: 10.1126/science.7280665. [DOI] [PubMed] [Google Scholar]

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