Skip to main content
Gut logoLink to Gut
. 1989 Jan;30(1):35–38. doi: 10.1136/gut.30.1.35

Intestinal transit in healthy southern Indian subjects and in patients with tropical sprue.

V Jayanthi 1, A Chacko 1, I K Gani 1, V I Mathan 1
PMCID: PMC1378227  PMID: 2920924

Abstract

Whole gut transit was measured in a group of 21 healthy volunteers and 21 patients with tropical sprue by radio-opaque marker technique, using mean transit time single (MTTS) and single stool transit (SST) method. Mean SST in controls was 25.8 (1.4) (SE) hours, which is considerably shorter than in controls in temperate zones. Mean SST (23.7 (0.6) h) correlated significantly with average MTTS (24.9 (1.6) h) (r = 0.88; p less than 0.001) confirming that SST is a valid method to measure intestinal transit in the tropics. Patients with tropical sprue had a mean SST similar to controls (24.4 (1.1) h), in spite of significantly higher faecal weights (580 (41.2) g v 252 (17.2) g; p less than 0.001).

Full text

PDF
35

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baker S. J., Jacob R., Mathan V. I. An evaluation of the 5 g D-xylose absorption test, with fractional urine collections, in subjects living in Southern India. Indian J Med Res. 1971 Dec;59(12):1869–1877. [PubMed] [Google Scholar]
  2. Baker S. J., Mathan V. I. Tropical enteropathy and tropical sprue. Am J Clin Nutr. 1972 Oct;25(10):1047–1055. doi: 10.1093/ajcn/25.10.1047. [DOI] [PubMed] [Google Scholar]
  3. Bingham S. A., Williams D. R., Cummings J. H. Dietary fibre consumption in Britain: new estimates and their relation to large bowel cancer mortality. Br J Cancer. 1985 Sep;52(3):399–402. doi: 10.1038/bjc.1985.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Burkitt D. P., Walker A. R., Painter N. S. Effect of dietary fibre on stools and the transit-times, and its role in the causation of disease. Lancet. 1972 Dec 30;2(7792):1408–1412. doi: 10.1016/s0140-6736(72)92974-1. [DOI] [PubMed] [Google Scholar]
  5. Chacko A., Begum A., Mathan V. I. Absorption of nutrient energy in southern Indian control subjects and patients with tropical sprue. Am J Clin Nutr. 1984 Oct;40(4):771–775. doi: 10.1093/ajcn/40.4.771. [DOI] [PubMed] [Google Scholar]
  6. Cook G. C. Delayed small-intestinal transit in tropical malabsorption. Br Med J. 1978 Jul 22;2(6132):238–240. doi: 10.1136/bmj.2.6132.238. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Cummings J. H., Jenkins D. J., Wiggins H. S. Measurement of the mean transit time of dietary residue through the human gut. Gut. 1976 Mar;17(3):210–218. doi: 10.1136/gut.17.3.210. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Cummings J. H., Wiggins H. S. Transit through the gut measured by analysis of a single stool. Gut. 1976 Mar;17(3):219–223. doi: 10.1136/gut.17.3.219. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Glober G. A., Klein K. L., Moore J. O., Abba B. C. Bowel transit-times in two populations experiencing similar colon-cancer risks. Lancet. 1974 Jul 13;2(7872):80–81. doi: 10.1016/s0140-6736(74)91638-9. [DOI] [PubMed] [Google Scholar]
  10. Holgate A. M., Read N. W. Relationship between small bowel transit time and absorption of a solid meal. Influence of metoclopramide, magnesium sulfate, and lactulose. Dig Dis Sci. 1983 Sep;28(9):812–819. doi: 10.1007/BF01296904. [DOI] [PubMed] [Google Scholar]
  11. Mathan V. I., Swarnabai S., Baker S. J. Intestinal absorption of radioactive vitamin B 12: a comparison of plasma, faecal and urinary tests. Indian J Med Res. 1973 May;61(5):714–723. [PubMed] [Google Scholar]
  12. Patowary A. G., Patowary S., Ahmed G. G. A study on intestinal transit time on healthy volunteers in Assam. Trop Gastroenterol. 1983 Apr-Jun;4(2):104–108. [PubMed] [Google Scholar]
  13. Ramakrishna B. S., Mathan V. I. Water and electrolyte absorption by the colon in tropical sprue. Gut. 1982 Oct;23(10):843–846. doi: 10.1136/gut.23.10.843. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Read N. W., McFarlane A., Kinsman R. I., Bates T. E., Blackhall N. W., Farrar G. B., Hall J. C., Moss G., Morris A. P., O'Neill B. Effect of infusion of nutrient solutions into the ileum on gastrointestinal transit and plasma levels of neurotensin and enteroglucagon. Gastroenterology. 1984 Feb;86(2):274–280. [PubMed] [Google Scholar]
  15. Read N. W., Miles C. A., Fisher D., Holgate A. M., Kime N. D., Mitchell M. A., Reeve A. M., Roche T. B., Walker M. Transit of a meal through the stomach, small intestine, and colon in normal subjects and its role in the pathogenesis of diarrhea. Gastroenterology. 1980 Dec;79(6):1276–1282. [PubMed] [Google Scholar]
  16. Shetty P. S., Kurpad A. V. Intestinal transit time of south Indian subjects. Indian J Med Res. 1984 Dec;80:693–698. [PubMed] [Google Scholar]
  17. Tandon R. K., Prasad N., Gupta M. C., Tandon B. N. Stool weights and transit time in North Indians. J Assoc Physicians India. 1976 Dec;24(12):807–810. [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES