Skip to main content
PMC home page
Gut logoLink to Gut
. 1990 Mar;31(3):329–333. doi: 10.1136/gut.31.3.329

Factors affecting colectomy rate in ulcerative colitis: an epidemiologic study.

C E Leijonmarck 1, P G Persson 1, G Hellers 1
PMCID: PMC1378277  PMID: 2323599

Abstract

Factors affecting colectomy rate were studied in a retrospective population based series of 1586 patients with ulcerative colitis, in Stockholm County during 1955-84. Five hundred and sixty eight patients (36%) had total colitis at diagnosis, 603 patients (38%) left sided colitis, and 397 patients (25%) proctitis. During a median period of observation of 13 years 514 patients were treated by colectomy. The five, 10, and 25 year cumulative colectomy rate were 20% (CI 18-22%), 28% (CI 26-30%), and 45% (CI 41-49%) respectively. The main factor affecting the colectomy rate was the extent of disease at diagnosis. Patients with total colitis showed a five, 10, and 25 year cumulative colectomy rate of 32% (CI 28-36%), 42% (CI 38-46%), and 65% (CI 58-72%) respectively. Ten per cent of the 1586 patients had a colectomy during the first year after diagnosis, 4% during the second year and 1% during subsequent years. The age at diagnosis and sex did not affect the cumulative colectomy rate. Elective colectomy was performed in 322 cases (63%) and acute colectomy in 192. The duration of disease before colectomy fell during the study period due to a more standardised criteria for colectomy in severe attacks. One hundred and twenty nine (66%) of the acute colectomies were performed within two years from diagnosis.

Full text

PDF
329

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bonnevie O., Binder V., Anthonisen P., Riis P. The prognosis of ulcerative colitis. Scand J Gastroenterol. 1974;9(1):81–91. [PubMed] [Google Scholar]
  2. Broström O., Löfberg R., Nordenvall B., Ost A., Hellers G. The risk of colorectal cancer in ulcerative colitis. An epidemiologic study. Scand J Gastroenterol. 1987 Dec;22(10):1193–1199. doi: 10.3109/00365528708996463. [DOI] [PubMed] [Google Scholar]
  3. Broström O., Löfberg R., Ost A., Reichard H. Cancer surveillance of patients with longstanding ulcerative colitis: a clinical, endoscopical, and histological study. Gut. 1986 Dec;27(12):1408–1413. doi: 10.1136/gut.27.12.1408. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. EDWARDS F. C., TRUELOVE S. C. THE COURSE AND PROGNOSIS OF ULCERATIVE COLITIS. Gut. 1963 Dec;4:299–315. doi: 10.1136/gut.4.4.299. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Gyde S. N., Prior P., Allan R. N., Stevens A., Jewell D. P., Truelove S. C., Lofberg R., Brostrom O., Hellers G. Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres. Gut. 1988 Feb;29(2):206–217. doi: 10.1136/gut.29.2.206. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Hendriksen C., Kreiner S., Binder V. Long term prognosis in ulcerative colitis--based on results from a regional patient group from the county of Copenhagen. Gut. 1985 Feb;26(2):158–163. doi: 10.1136/gut.26.2.158. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Leijonmarck C. E., Broström O., Monsen U., Hellers G. Surgical treatment of ulcerative colitis in Stockholm County, 1955 to 1984. Dis Colon Rectum. 1989 Nov;32(11):918–926. doi: 10.1007/BF02552266. [DOI] [PubMed] [Google Scholar]
  8. Nordenvall B., Broström O., Berglund M., Monsen U., Nordenström J., Sörstad J., Hellers G. Incidence of ulcerative colitis in Stockholm County 1955-1979. Scand J Gastroenterol. 1985 Sep;20(7):783–790. doi: 10.3109/00365528509088823. [DOI] [PubMed] [Google Scholar]
  9. Powell-Tuck J., Ritchie J. K., Lennard-Jones J. E. The prognosis of idiopathic proctitis. Scand J Gastroenterol. 1977;12(6):727–732. doi: 10.3109/00365527709181711. [DOI] [PubMed] [Google Scholar]
  10. Ritchie J. K., Powell-Tuck J., Lennard-Jones J. E. Clinical outcome of the first ten years of ulcerative colitis and proctitis. Lancet. 1978 May 27;1(8074):1140–1143. doi: 10.1016/s0140-6736(78)90312-4. [DOI] [PubMed] [Google Scholar]
  11. Sinclair T. S., Brunt P. W., Mowat N. A. Nonspecific proctocolitis in northeastern Scotland: a community study. Gastroenterology. 1983 Jul;85(1):1–11. [PubMed] [Google Scholar]
  12. Truelove S. C., Jewell D. P. Intensive intravenous regimen for severe attacks of ulcerative colitis. Lancet. 1974 Jun 1;1(7866):1067–1070. doi: 10.1016/s0140-6736(74)90552-2. [DOI] [PubMed] [Google Scholar]
  13. Watts J. M., De Dombal F. T., Watkinson G., Goligher J. C. Early course of ulcerative colitis. Gut. 1966 Feb;7(1):16–31. doi: 10.1136/gut.7.1.16. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES