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. 1990 May;31(5):514–517. doi: 10.1136/gut.31.5.514

Abolition by omeprazole of aspirin induced gastric mucosal injury in man.

T K Daneshmend 1, A G Stein 1, N K Bhaskar 1, C J Hawkey 1
PMCID: PMC1378564  PMID: 2190865

Abstract

This study investigates whether aspirin injury to the human gastric mucosa can be prevented by profound acid suppression with omeprazole, in a randomised, double blind, crossover design according to latin square. It was concluded that profound acid suppression can prevent aspirin induced gastric mucosal injury in normal subjects. This approach may prevent the development of peptic ulcers and their complications in patients taking aspirin and other non-steroidal anti-inflammatory drugs.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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