Abstract
This study was undertaken to investigate the extent to which gastric electrical control activity and phasic contractile activity are preserved after Billroth II resection and to assess the relation between these activities and postprandial symptoms in patients who have undergone Billroth II resection. Thirty three patients were studied after Billroth II resection without vagotomy. Gastric electrical activity was recorded from surface electrodes and intraluminal pressure was recorded simultaneously. The electrogastrographic signals were analysed by Running Spectrum Analysis. In addition, three dogs with a Billroth II stomach and implanted serosal electrodes were studied. Phasic gastric pressure waves were observed in most patients. Electrogastrographic signals recorded from 82% of the Billroth II patients contained a mean (SD) peak at 3.1 (0.2) cycles per minute (cpm). Fasting and postprandial frequencies correlated significantly (p less than 0.02) with the score for nausea and vomiting. In 61% of the patients, the electrogastrographic signal contained a stable component with a frequency of 10.5 (0.6) cpm that was not caused by respiration. We suggest that this activity is of intestinal origin. In all three dogs studied, retrograde conduction of jejunal electrical control activity (16 cpm) into the distal part of the gastric remnant was observed. In the Billroth II patients, the presence of a 10 cpm component correlated negatively with symptoms.
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- Abell T. L., Malagelada J. R. Electrogastrography. Current assessment and future perspectives. Dig Dis Sci. 1988 Aug;33(8):982–992. doi: 10.1007/BF01535995. [DOI] [PubMed] [Google Scholar]
- Cox A. G. Comparison of symptoms after vagotomy with gastrojejunostomy and partial gastrectomy. Br Med J. 1968 Feb 3;1(5587):288–290. doi: 10.1136/bmj.1.5587.288. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Geldof H., van der Schee E. J., van Blankenstein M., Grashuis J. L. Electrogastrographic study of gastric myoelectrical activity in patients with unexplained nausea and vomiting. Gut. 1986 Jul;27(7):799–808. doi: 10.1136/gut.27.7.799. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Heading R. C., Tothill P., McLoughlin G. P., Shearman D. J. Gastric emptying rate measurement in man. A double isotope scanning technique for simultaneous study of liquid and solid components of a meal. Gastroenterology. 1976 Jul;71(1):45–50. [PubMed] [Google Scholar]
- Hinder R. A., Kelly K. A. Human gastric pacesetter potential. Site of origin, spread, and response to gastric transection and proximal gastric vagotomy. Am J Surg. 1977 Jan;133(1):29–33. doi: 10.1016/0002-9610(77)90187-8. [DOI] [PubMed] [Google Scholar]
- Kelly K. A., Code C. F., Elveback L. R. Patterns of canine gastric electrical activity. Am J Physiol. 1969 Aug;217(2):461–470. doi: 10.1152/ajplegacy.1969.217.2.461. [DOI] [PubMed] [Google Scholar]
- MacGregor I. L., Martin P., Meyer J. H. Gastric emptying of solid food in normal man and after subtotal gastrectomy and truncal vagotomy with pyloroplasty. Gastroenterology. 1977 Feb;72(2):206–211. [PubMed] [Google Scholar]
- Malmud L. S., Fisher R. S. Scintigraphic evaluation of disorders of the esophagus, stomach, and duodenum. Med Clin North Am. 1981 Nov;65(6):1291–1310. doi: 10.1016/s0025-7125(16)31473-0. [DOI] [PubMed] [Google Scholar]
- Nelsen T. S., Kohatsu S. Clinical electrogastrography and its relationship to gastric surgery. Am J Surg. 1968 Aug;116(2):215–222. doi: 10.1016/0002-9610(68)90496-0. [DOI] [PubMed] [Google Scholar]
- Sarna S. K. Gastrointestinal electrical activity: terminology. Gastroenterology. 1975 Jun;68(6):1631–1635. [PubMed] [Google Scholar]
- Smout A. J., Akkermans L. M., Roelofs J. M., Pasma F. G., Oei H. Y., Wittebol P. Gastric emptying and postprandial symptoms after Billroth II resection. Surgery. 1987 Jan;101(1):27–34. [PubMed] [Google Scholar]
- Smout A. J., van der Schee E. J., Grashuis J. L. What is measured in electrogastrography? Dig Dis Sci. 1980 Mar;25(3):179–187. doi: 10.1007/BF01308136. [DOI] [PubMed] [Google Scholar]
- Weber J., Jr, Koatsu S. Pacemaker localization and electrical conduction patterns in the canine stomach. Gastroenterology. 1970 Nov;59(5):717–726. [PubMed] [Google Scholar]
- el-Sharkawy T. Y., Morgan K. G., Szurszewski J. H. Intracellular electrical activity of canine and human gastric smooth muscle. J Physiol. 1978 Jun;279:291–307. doi: 10.1113/jphysiol.1978.sp012345. [DOI] [PMC free article] [PubMed] [Google Scholar]

