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. 1990 Dec;31(12):1411–1413. doi: 10.1136/gut.31.12.1411

Ethanol in pancreatic juice after oral and intravenous administration.

I Gjørup 1, S Dueholm 1, B Andersen 1, F Burcharth 1
PMCID: PMC1378767  PMID: 2265784

Abstract

Six patients with a drain in the main pancreatic duct were studied. Ethanol was given orally with individually adjusted doses aiming at a blood value of 0.8/1000 (17.6 mmol/l). Concentrations of ethanol in venous blood and pancreatic juice were recorded for three hours. Similar studies were made when ethanol was administered as an intravenous priming dose followed by a maintenance infusion. After orally administered ethanol, pancreatic juice values were higher than those in blood for a short period of time. The relations between median concentrations and time were incongruous curves consistent with a significant treatment by time interaction. Intravenous administration resulted in a similar pattern, but the interaction was not statistically significant. These findings indicate that the human pancreas may secrete ethanol.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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