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. 1991 Nov;32(11):1421–1425. doi: 10.1136/gut.32.11.1421

Response to autoimmune enteropathy to cyclosporin A therapy.

I R Sanderson 1, A D Phillips 1, J Spencer 1, J A Walker-Smith 1
PMCID: PMC1379182  PMID: 1752480

Abstract

Small bowel enteropathies that are associated with an autoimmune process are often resistant to treatment. Two children with autoimmune enteropathy were treated with cyclosporin A for eight months. Both improved, as assessed by growth, small intestinal mucosal morphology, and carbohydrate absorption. Cyclosporin A is useful in the treatment of autoimmune enteropathy. This report also suggests that T cell activation (which is suppressed by cyclosporin A) is important in the pathogenesis of this condition.

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Selected References

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