Abstract
Results of continuous 12 hour overnight pH monitoring (duration of pH less than 4) were reviewed in 112 patients with heartburn or regurgitation, or both, and in 56 normal subjects. Patients had more reflux than normal subjects. Medically controlled patients (n = 51) had less acid reflux than patients who subsequently underwent reflux surgery (n = 61), but there was a considerable overlap between those two groups. Surgery was followed by a reduction in acid reflux to a value similar to that in normal subjects. Patients in whom surgery was deemed to have failed had more reflux after the operation than those in whom it was successful, but no difference could be found in the preoperative reflux values of these two subgroups. Monitoring pH is not of value in selecting candidates for surgery since the results are not a good predictor of outcome, but it is useful in the objective evaluation of surgical results.
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Selected References
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- Boesby S., Madsen T., Sörensen H. R. Gastro-oesophageal acid reflux. Method for 12-hour continuous recording of oesophageal pH with analysis of records. Scand J Gastroenterol. 1975;10(4):379–384. [PubMed] [Google Scholar]
- Branicki F. J., Evans D. F., Ogilvie A. L., Atkinson M., Hardcastle J. D. Ambulatory monitoring of oesophageal pH in reflux oesophagitis using a portable radiotelemetry system. Gut. 1982 Nov;23(11):992–998. doi: 10.1136/gut.23.11.992. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Demeester T. R., Johnson L. F., Kent A. H. Evaluation of current operations for the prevention of gastroesophageal reflux. Ann Surg. 1974 Oct;180(4):511–525. doi: 10.1097/00000658-197410000-00016. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gear M. W., Gillison E. W., Dowling B. L. Randomized prospective trial of the Angelchik anti-reflux prosthesis. Br J Surg. 1984 Sep;71(9):681–683. doi: 10.1002/bjs.1800710911. [DOI] [PubMed] [Google Scholar]
- Johnson L. F., Demeester T. R. Twenty-four-hour pH monitoring of the distal esophagus. A quantitative measure of gastroesophageal reflux. Am J Gastroenterol. 1974 Oct;62(4):325–332. [PubMed] [Google Scholar]
- Johnsson F., Joelsson B., Gudmundsson K., Florén C. H., Walther B. Effects of fundoplication on the antireflux mechanism. Br J Surg. 1987 Dec;74(12):1111–1114. doi: 10.1002/bjs.1800741212. [DOI] [PubMed] [Google Scholar]
- Johnsson F., Joelsson B., Gudmundsson K., Greiff L. Symptoms and endoscopic findings in the diagnosis of gastroesophageal reflux disease. Scand J Gastroenterol. 1987 Aug;22(6):714–718. doi: 10.3109/00365528709011148. [DOI] [PubMed] [Google Scholar]
- Johnsson F., Joelsson B., Isberg P. E. Ambulatory 24 hour intraesophageal pH-monitoring in the diagnosis of gastroesophageal reflux disease. Gut. 1987 Sep;28(9):1145–1150. doi: 10.1136/gut.28.9.1145. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Richter J. E., Castell D. O. Gastroesophageal reflux. Pathogenesis, diagnosis, and therapy. Ann Intern Med. 1982 Jul;97(1):93–103. doi: 10.7326/0003-4819-97-1-93. [DOI] [PubMed] [Google Scholar]
- Stanciu C., Hoare R. C., Bennett J. R. Correlation between manometric and pH tests for gastro-oesophageal reflux. Gut. 1977 Jul;18(7):536–540. doi: 10.1136/gut.18.7.536. [DOI] [PMC free article] [PubMed] [Google Scholar]
