Skip to main content
Gut logoLink to Gut
. 1992 Sep;33(9):1159–1161. doi: 10.1136/gut.33.9.1159

Comparison of endoscopic injection therapy versus the heater probe in major peptic ulcer haemorrhage.

C P Choudari 1, C Rajgopal 1, K R Palmer 1
PMCID: PMC1379477  PMID: 1427365

Abstract

One hundred and twenty patients presenting with major peptic ulcer haemorrhage were randomised in a clinical trial comparing endoscopic injection and heater probe therapy. The two groups were well matched with regards to age, admission haemoglobin concentration, the presence of shock, non-steroidal anti-inflammatory drug usage and endoscopic findings. Permanent haemostasis was achieved in 87% of the injection group and 85% of the heater probe group. Hospital mortality, transfusion requirement and duration of admission were similar in both groups. Endoscopic injection and the heater probe represent equally effective therapy for peptic ulcer bleeding.

Full text

PDF
1159

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chung S. C., Leung J. W., Steele R. J., Crofts T. J., Li A. K. Endoscopic injection of adrenaline for actively bleeding ulcers: a randomised trial. Br Med J (Clin Res Ed) 1988 Jun 11;296(6637):1631–1633. doi: 10.1136/bmj.296.6637.1631. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Chung S. C., Leung J. W., Sung J. Y., Lo K. K., Li A. K. Injection or heat probe for bleeding ulcer. Gastroenterology. 1991 Jan;100(1):33–37. doi: 10.1016/0016-5085(91)90579-a. [DOI] [PubMed] [Google Scholar]
  3. Foster D. N., Miloszewski K. J., Losowsky M. S. Stigmata of recent haemorrhage in diagnosis and prognosis of upper gastrointestinal bleeding. Br Med J. 1978 May 6;1(6121):1173–1177. doi: 10.1136/bmj.1.6121.1173. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Leung J. W., Chung S. C. Endoscopic injection of adrenalin in bleeding peptic ulcers. Gastrointest Endosc. 1987 Apr;33(2):73–75. doi: 10.1016/s0016-5107(87)71512-0. [DOI] [PubMed] [Google Scholar]
  5. Levy J., Khakoo S., Barton R., Vicary R. Fatal injection sclerotherapy of a bleeding peptic ulcer. Lancet. 1991 Feb 23;337(8739):504–504. doi: 10.1016/0140-6736(91)93452-f. [DOI] [PubMed] [Google Scholar]
  6. Lin H. J., Lee F. Y., Kang W. M., Tsai Y. T., Lee S. D., Lee C. H. Heat probe thermocoagulation and pure alcohol injection in massive peptic ulcer haemorrhage: a prospective, randomised controlled trial. Gut. 1990 Jul;31(7):753–757. doi: 10.1136/gut.31.7.753. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Panés J., Viver J., Forné M., Garcia-Olivares E., Marco C., Garau J. Controlled trial of endoscopic sclerosis in bleeding peptic ulcers. Lancet. 1987 Dec 5;2(8571):1292–1294. doi: 10.1016/s0140-6736(87)91191-3. [DOI] [PubMed] [Google Scholar]
  8. Rajgopal C., Palmer K. R. Endoscopic injection sclerosis: effective treatment for bleeding peptic ulcer. Gut. 1991 Jul;32(7):727–729. doi: 10.1136/gut.32.7.727. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Rutgeerts P., Geboes K., Vantrappen G. Experimental studies of injection therapy for severe nonvariceal bleeding in dogs. Gastroenterology. 1989 Sep;97(3):610–621. doi: 10.1016/0016-5085(89)90632-x. [DOI] [PubMed] [Google Scholar]
  10. Shorvon P. J., Leung J. W., Cotton P. B. Preliminary clinical experience with the heat probe at endoscopy in acute upper gastrointestinal bleeding. Gastrointest Endosc. 1985 Dec;31(6):364–366. doi: 10.1016/s0016-5107(85)72248-1. [DOI] [PubMed] [Google Scholar]
  11. Sugawa C., Fujita Y., Ikeda T., Walt A. J. Endoscopic hemostasis of bleeding of the upper gastrointestinal tract by local injection of ninety-eight per cent dehydrated ethanol. Surg Gynecol Obstet. 1986 Feb;162(2):159–163. [PubMed] [Google Scholar]
  12. Wördehoff D., Gros H. Endoscopic haemostasis by injection-therapy in high-risk patients. Endoscopy. 1982 Nov;14(6):196–199. doi: 10.1055/s-2007-1021620. [DOI] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES