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. 1992 Oct;33(10):1424–1426. doi: 10.1136/gut.33.10.1424

Non-steroidal anti-inflammatory drug-induced jejunal and colonic diaphragm disease: a report of two cases.

I W Fellows 1, J M Clarke 1, P F Roberts 1
PMCID: PMC1379618  PMID: 1446874

Abstract

Two patients with intestinal submucosal diaphragm disease associated with non-steroidal anti-inflammatory drugs are presented. The jejunum was affected in one, and in the other the ascending colon. Most previously reported cases have shown ileal disease and no case to date has shown involvement of the colon. The reasons for the localisation of these diaphragms remain unclear.

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Selected References

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  1. Aabakken L., Osnes M. Non-steroidal anti-inflammatory drug-induced disease in the distal ileum and large bowel. Scand J Gastroenterol Suppl. 1989;163:48–55. doi: 10.3109/00365528909091175. [DOI] [PubMed] [Google Scholar]
  2. Bjarnason I., Macpherson A. The changing gastrointestinal side effect profile of non-steroidal anti-inflammatory drugs. A new approach for the prevention of a new problem. Scand J Gastroenterol Suppl. 1989;163:56–64. doi: 10.3109/00365528909091176. [DOI] [PubMed] [Google Scholar]
  3. Bjarnason I., Price A. B., Zanelli G., Smethurst P., Burke M., Gumpel J. M., Levi A. J. Clinicopathological features of nonsteroidal antiinflammatory drug-induced small intestinal strictures. Gastroenterology. 1988 Apr;94(4):1070–1074. doi: 10.1016/0016-5085(88)90568-9. [DOI] [PubMed] [Google Scholar]
  4. De Vos M., Cuvelier C., Mielants H., Veys E., Barbier F., Elewaut A. Ileocolonoscopy in seronegative spondylarthropathy. Gastroenterology. 1989 Feb;96(2 Pt 1):339–344. doi: 10.1016/0016-5085(89)91557-6. [DOI] [PubMed] [Google Scholar]
  5. Jenkins A. P., Trew D. R., Crump B. J., Nukajam W. S., Foley J. A., Menzies I. S., Creamer B. Do non-steroidal anti-inflammatory drugs increase colonic permeability? Gut. 1991 Jan;32(1):66–69. doi: 10.1136/gut.32.1.66. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Lang J., Price A. B., Levi A. J., Burke M., Gumpel J. M., Bjarnason I. Diaphragm disease: pathology of disease of the small intestine induced by non-steroidal anti-inflammatory drugs. J Clin Pathol. 1988 May;41(5):516–526. doi: 10.1136/jcp.41.5.516. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Sturges H. F., Krone C. L. Ulceration and stricture of the jejunum in a patient on long-term indomethacin therapy. Am J Gastroenterol. 1973 Feb;59(2):162–169. [PubMed] [Google Scholar]
  8. Uribe A., Johansson C., Slezak P., Rubio C. Ulcerations of the colon associated with naproxen and acetylsalicylic acid treatment. Gastrointest Endosc. 1986 Jun;32(3):242–244. doi: 10.1016/s0016-5107(86)71824-5. [DOI] [PubMed] [Google Scholar]

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