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. 1992 Oct;33(10):1436–1438. doi: 10.1136/gut.33.10.1436

Piroxicam induced submassive necrosis of the liver.

D Paterson 1, P Kerlin 1, N Walker 1, S Lynch 1, R Strong 1
PMCID: PMC1379622  PMID: 1446877

Abstract

Several widely used non-steroidal anti-inflammatory drugs have been reported as causing severe hepatitis. Three cases of severe acute hepatitis have been reported in association with piroxicam. A fatal submassive necrosis that occurred in a 68 year old lady who had received piroxicam for 15 months is described. A 48 year old man who developed submassive hepatic necrosis six weeks after beginning piroxicam but was successfully treated with orthotopic liver transplantation is also reported. Piroxicam may induce submassive necrosis of the liver, probably as an idiosyncratic reaction.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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