Abstract
There have been significant developments in epidemiologic methodology during the past century, including changes in basic concepts, methods of data analysis, and methods of exposure measurement. However, the rise of modern epidemiology has been a mixed blessing, and the new paradigm has major shortcomings, both in public health and in scientific terms. The changes in the paradigm have not been neutral but have rather helped change--and have reflected changes in--the way in which epidemiologists think about health and disease. The key issue has been the shift in the level of analysis from the population to the individual. Epidemiology has largely ceased to function as part of a multidisciplinary approach to understanding the causation of disease in populations and has become a set of generic methods for measuring associations of exposure and disease in individuals. This reductionist approach focuses on the individual, blames the victim, and produces interventions that can be harmful. We seem to be using more and more advanced technology to study more and more trivial issues, while the major causes of disease are ignored. Epidemiology must reintegrate itself into public health and must rediscover the population perspective.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Adler N. E., Boyce W. T., Chesney M. A., Folkman S., Syme S. L. Socioeconomic inequalities in health. No easy solution. JAMA. 1993 Jun 23;269(24):3140–3145. [PubMed] [Google Scholar]
- Barry M. The influence of the U.S. tobacco industry on the health, economy, and environment of developing countries. N Engl J Med. 1991 Mar 28;324(13):917–920. doi: 10.1056/NEJM199103283241311. [DOI] [PubMed] [Google Scholar]
- Black D. Deprivation and health. BMJ. 1993 Dec 18;307(6919):1630–1631. doi: 10.1136/bmj.307.6919.1630. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cameron D., Jones I. G. John Snow, the broad street pump and modern epidemiology. Int J Epidemiol. 1983 Dec;12(4):393–396. doi: 10.1093/ije/12.4.393. [DOI] [PubMed] [Google Scholar]
- Cassel J. The contribution of the social environment to host resistance: the Fourth Wade Hampton Frost Lecture. Am J Epidemiol. 1976 Aug;104(2):107–123. doi: 10.1093/oxfordjournals.aje.a112281. [DOI] [PubMed] [Google Scholar]
- Dean K. Creating a new knowledge base for the new public health. J Epidemiol Community Health. 1994 Jun;48(3):217–219. doi: 10.1136/jech.48.3.217-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Firth W. J. Chaos--predicting the unpredictable. BMJ. 1991 Dec 21;303(6817):1565–1568. doi: 10.1136/bmj.303.6817.1565. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Greenland S., Robins J. Invited commentary: ecologic studies--biases, misconceptions, and counterexamples. Am J Epidemiol. 1994 Apr 15;139(8):747–760. doi: 10.1093/oxfordjournals.aje.a117069. [DOI] [PubMed] [Google Scholar]
- Koopman J. S., Longini I. M., Jr The ecological effects of individual exposures and nonlinear disease dynamics in populations. Am J Public Health. 1994 May;84(5):836–842. doi: 10.2105/ajph.84.5.836. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Krieger N. Epidemiology and the web of causation: has anyone seen the spider? Soc Sci Med. 1994 Oct;39(7):887–903. doi: 10.1016/0277-9536(94)90202-x. [DOI] [PubMed] [Google Scholar]
- Lilienfeld A. M., Lilienfeld D. E. Epidemiology and the public health movement: a historical perspective. J Public Health Policy. 1982 Jun;3(2):140–149. [PubMed] [Google Scholar]
- Lilienfeld D. E., Lilienfeld A. M. Epidemiology: a retrospective study. Am J Epidemiol. 1977 Dec;106(6):445–459. doi: 10.1093/oxfordjournals.aje.a112490. [DOI] [PubMed] [Google Scholar]
- Loomis D., Wing S. Is molecular epidemiology a germ theory for the end of the twentieth century? Int J Epidemiol. 1990 Mar;19(1):1–3. doi: 10.1093/ije/19.1.1. [DOI] [PubMed] [Google Scholar]
- McKinlay J. B. The promotion of health through planned sociopolitical change: challenges for research and policy. Soc Sci Med. 1993 Jan;36(2):109–117. doi: 10.1016/0277-9536(93)90202-f. [DOI] [PubMed] [Google Scholar]
- McMichael A. J. Invited commentary--"molecular epidemiology": new pathway or new travelling companion? Am J Epidemiol. 1994 Jul 1;140(1):1–11. doi: 10.1093/oxfordjournals.aje.a117153. [DOI] [PubMed] [Google Scholar]
- Millard A. V. A causal model of high rates of child mortality. Soc Sci Med. 1994 Jan;38(2):253–268. doi: 10.1016/0277-9536(94)90395-6. [DOI] [PubMed] [Google Scholar]
- Pappas G., Queen S., Hadden W., Fisher G. The increasing disparity in mortality between socioeconomic groups in the United States, 1960 and 1986. N Engl J Med. 1993 Jul 8;329(2):103–109. doi: 10.1056/NEJM199307083290207. [DOI] [PubMed] [Google Scholar]
- Pearce N. E., Davis P. B., Smith A. H., Foster F. H. Social class, ethnic group, and male mortality in New Zealand, 1974-8. J Epidemiol Community Health. 1985 Mar;39(1):9–14. doi: 10.1136/jech.39.1.9. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pearce N. Economic policy and health in the year of the family. N Z Med J. 1994 Sep 28;107(986 Pt 1):379–381. [PubMed] [Google Scholar]
- Pearce N., de Sanjose S., Boffetta P., Kogevinas M., Saracci R., Savitz D. Limitations of biomarkers of exposure in cancer epidemiology. Epidemiology. 1995 Mar;6(2):190–194. doi: 10.1097/00001648-199503000-00020. [DOI] [PubMed] [Google Scholar]
- Potter J. D. Reconciling the epidemiology, physiology, and molecular biology of colon cancer. JAMA. 1992 Sep 23;268(12):1573–1577. [PubMed] [Google Scholar]
- Smith G. D., Morris J. Increasing inequalities in the health of the nation. BMJ. 1994 Dec 3;309(6967):1453–1454. doi: 10.1136/bmj.309.6967.1453. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stallones R. A. To advance epidemiology. Annu Rev Public Health. 1980;1:69–82. doi: 10.1146/annurev.pu.01.050180.000441. [DOI] [PubMed] [Google Scholar]
- Susser M. Epidemiology in the United States after World War II: the evolution of technique. Epidemiol Rev. 1985;7:147–177. doi: 10.1093/oxfordjournals.epirev.a036280. [DOI] [PubMed] [Google Scholar]
- Susser M. Epidemiology today: 'a thought-tormented world'. Int J Epidemiol. 1989 Sep;18(3):481–488. doi: 10.1093/ije/18.3.481. [DOI] [PubMed] [Google Scholar]
- Susser M. The logic in ecological: II. The logic of design. Am J Public Health. 1994 May;84(5):830–835. doi: 10.2105/ajph.84.5.830. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Syme S. L., Berkman L. F. Social class, susceptibility and sickness. Am J Epidemiol. 1976 Jul;104(1):1–8. doi: 10.1093/oxfordjournals.aje.a112268. [DOI] [PubMed] [Google Scholar]
- Terris M. Epidemiology and the public health movement. J Public Health Policy. 1987 Autumn;8(3):315–329. [PubMed] [Google Scholar]
- Vandenbroucke J. P. New public health and old rhetoric. BMJ. 1994 Apr 16;308(6935):994–995. doi: 10.1136/bmj.308.6935.994. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wilkinson R. G. National mortality rates: the impact of inequality? Am J Public Health. 1992 Aug;82(8):1082–1084. doi: 10.2105/ajph.82.8.1082. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wing S. Social inequalities in the decline of coronary mortality. Am J Public Health. 1988 Nov;78(11):1415–1416. doi: 10.2105/ajph.78.11.1415. [DOI] [PMC free article] [PubMed] [Google Scholar]