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American Journal of Public Health logoLink to American Journal of Public Health
. 1997 Jun;87(6):1008–1012. doi: 10.2105/ajph.87.6.1008

Reduced probability of HIV infection among crack cocaine--using injection drug users.

M Y Iguchi 1, D A Bux Jr 1
PMCID: PMC1380939  PMID: 9224185

Abstract

OBJECTIVES: This study examined in greater detail the authors' previously reported finding that crack use among injection drug users is associated with lower levels of infection with the human immunodeficiency virus (HIV). METHODS: Self-reported data and blood tests for HIV antibodies from 4840 out-of-treatment injection drug users were used to examine relationships among crack use, HIV risk behavior, and HIV infection. RESULTS: Crack use was significantly associated with higher levels of many sexual risk and needle use behaviors and was consistently associated, independently of all behavioral variables examined, with lower rates of HIV infection. CONCLUSIONS: Crack use among injection drug users appears to be associated with lower risk for HIV infection independently of other behavioral variables.

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Selected References

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  1. Anthony J. C., Vlahov D., Nelson K. E., Cohn S., Astemborski J., Solomon L. New evidence on intravenous cocaine use and the risk of infection with human immunodeficiency virus type 1. Am J Epidemiol. 1991 Nov 15;134(10):1175–1189. doi: 10.1093/oxfordjournals.aje.a116021. [DOI] [PubMed] [Google Scholar]
  2. Blower S. M., McLean A. R. Mixing ecology and epidemiology. Proc Biol Sci. 1991 Sep 23;245(1314):187–192. doi: 10.1098/rspb.1991.0108. [DOI] [PubMed] [Google Scholar]
  3. Booth R. E., Watters J. K., Chitwood D. D. HIV risk-related sex behaviors among injection drug users, crack smokers, and injection drug users who smoke crack. Am J Public Health. 1993 Aug;83(8):1144–1148. doi: 10.2105/ajph.83.8.1144. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bux D. A., Lamb R. J., Iguchi M. Y. Cocaine use and HIV risk behavior in methadone maintenance patients. Drug Alcohol Depend. 1995 Jan;37(1):29–35. doi: 10.1016/0376-8716(94)01058-s. [DOI] [PubMed] [Google Scholar]
  5. Caussy D., Weiss S. H., Blattner W. A., French J., Cantor K. P., Ginzburg H., Altman R., Goedert J. J. Exposure factors for HIV-1 infection among heterosexual drug abusers in New Jersey treatment programs. AIDS Res Hum Retroviruses. 1990 Dec;6(12):1459–1467. doi: 10.1089/aid.1990.6.1459. [DOI] [PubMed] [Google Scholar]
  6. Chaisson R. E., Bacchetti P., Osmond D., Brodie B., Sande M. A., Moss A. R. Cocaine use and HIV infection in intravenous drug users in San Francisco. JAMA. 1989 Jan 27;261(4):561–565. [PubMed] [Google Scholar]
  7. Des Jarlais D. C., Wenston J., Friedman S. R., Sotheran J. L., Maslansky R., Marmor M. Crack cocaine use in a cohort of methadone maintenance patients. J Subst Abuse Treat. 1992 Fall;9(4):319–325. doi: 10.1016/0740-5472(92)90025-j. [DOI] [PubMed] [Google Scholar]
  8. Donoghoe M. C., Dolan K. A., Stimson G. V. Life-style factors and social circumstances of syringe sharing in injecting drug users. Br J Addict. 1992 Jul;87(7):993–1003. doi: 10.1111/j.1360-0443.1992.tb03116.x. [DOI] [PubMed] [Google Scholar]
  9. Iguchi M. Y., Bux D. A., Lidz V., Kushner H., French J. F., Platt J. J. Interpreting HIV seroprevalence data from a street-based outreach program. J Acquir Immune Defic Syndr. 1994 May;7(5):491–499. [PubMed] [Google Scholar]
  10. McBride D. C., Inciardi J. A., Chitwood D. D., McCoy C. B. Crack use and correlates of use in a national population of street heroin users. The National AIDS Research Consortium. J Psychoactive Drugs. 1992 Oct-Dec;24(4):411–416. doi: 10.1080/02791072.1992.10471665. [DOI] [PubMed] [Google Scholar]
  11. Novick D. M., Trigg H. L., Des Jarlais D. C., Friedman S. R., Vlahov D., Kreek M. J. Cocaine injection and ethnicity in parenteral drug users during the early years of the human immunodeficiency virus (HIV) epidemic in New York City. J Med Virol. 1989 Nov;29(3):181–185. doi: 10.1002/jmv.1890290307. [DOI] [PubMed] [Google Scholar]
  12. Schoenbaum E. E., Hartel D., Selwyn P. A., Klein R. S., Davenny K., Rogers M., Feiner C., Friedland G. Risk factors for human immunodeficiency virus infection in intravenous drug users. N Engl J Med. 1989 Sep 28;321(13):874–879. doi: 10.1056/NEJM198909283211306. [DOI] [PubMed] [Google Scholar]
  13. Service S. k., Blower S. M. HIV transmission in sexual networks: an empirical analysis. Proc Biol Sci. 1995 Jun 22;260(1359):237–244. doi: 10.1098/rspb.1995.0086. [DOI] [PubMed] [Google Scholar]
  14. Wolfe H., Vranizan K. M., Gorter R. G., Keffelew A. S., Moss A. R. Crack use and human immunodeficiency virus infection among San Francisco intravenous drug users. Sex Transm Dis. 1992 Mar-Apr;19(2):111–114. [PubMed] [Google Scholar]

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