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. 1992 Sep;34(3):272–274. doi: 10.1111/j.1365-2125.1992.tb04137.x

Beta-adrenoceptor antagonists enhance white blood cell aggregation in patients with ischaemic heart disease.

A B Bridges 1, T H Pringle 1, G P McNeill 1, R Tavendale 1, J J Belch 1
PMCID: PMC1381401  PMID: 1356405

Abstract

The effects of beta-adrenoceptor antagonists, calcium channel blockers and long acting nitrates on white blood cell (WBC) aggregation were studied in patients with ischaemic heart disease. WBC aggregation was significantly increased by beta-adrenoceptor antagonists (P = 0.011) but was unaffected by either calcium channel blockers or long acting nitrates. Enhanced WBC aggregation promotes microvascular occlusion and damage.

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Selected References

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