Abstract
Fifty six patients with gall stones were enrolled in this study to assess the presence of Helicobacter pylori in gastric mucosa before and after cholecystectomy. Samples were taken from gastric juice and antral mucosa through endoscopy performed on these patients before and after the operation. Gastric juice was examined for bile salt concentration as an indicator of duodenogastric reflux. Antral mucosa was studied for the presence of H pylori and inflammatory response. Duodenogastric reflux was significantly increased (p < 0.001) and H pylori significantly decreased (p < 0.01) in the postoperative period. Mucosal inflammation and its activity were less in the postoperative period but the differences did not reach statistically significant values.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Buch K. L., Weinstein W. M., Hill T. A., Elashoff J. D., Reedy T. J., Ippoliti A. F., Tedesco F. J., Singh M. Sucralfate therapy in patients with symptoms of alkaline reflux gastritis. A randomized, double-blind study. Am J Med. 1985 Aug 30;79(2C):49–54. doi: 10.1016/0002-9343(85)90573-x. [DOI] [PubMed] [Google Scholar]
- Buck G. E., Gourley W. K., Lee W. K., Subramanyam K., Latimer J. M., DiNuzzo A. R. Relation of Campylobacter pyloridis to gastritis and peptic ulcer. J Infect Dis. 1986 Apr;153(4):664–669. doi: 10.1093/infdis/153.4.664. [DOI] [PubMed] [Google Scholar]
- Diehl A. K. Symptoms of gallstone disease. Baillieres Clin Gastroenterol. 1992 Nov;6(4):635–657. doi: 10.1016/0950-3528(92)90044-f. [DOI] [PubMed] [Google Scholar]
- Feng Y. Y., Wang Y. Campylobacter pylori in patients with gastritis, peptic ulcer, and carcinoma of the stomach in Lanzhou, China. Lancet. 1988 May 7;1(8593):1055–1055. doi: 10.1016/s0140-6736(88)91877-6. [DOI] [PubMed] [Google Scholar]
- Fiocca R., Villani L., Turpini F., Turpini R., Solcia E. High incidence of Campylobacter-like organisms in endoscopic biopsies from patients with gastritis, with or without peptic ulcer. Digestion. 1987;38(4):234–244. doi: 10.1159/000199597. [DOI] [PubMed] [Google Scholar]
- Glambek I., Arnesjø B., Søreide O. Correlation between gallstones and abdominal symptoms in a random population. Results from a screening study. Scand J Gastroenterol. 1989 Apr;24(3):277–281. doi: 10.3109/00365528909093046. [DOI] [PubMed] [Google Scholar]
- Goodwin C. S., Armstrong J. A., Marshall B. J. Campylobacter pyloridis, gastritis, and peptic ulceration. J Clin Pathol. 1986 Apr;39(4):353–365. doi: 10.1136/jcp.39.4.353. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Goodwin C. S., Blincow E. D., Warren J. R., Waters T. E., Sanderson C. R., Easton L. Evaluation of cultural techniques for isolating Campylobacter pyloridis from endoscopic biopsies of gastric mucosa. J Clin Pathol. 1985 Oct;38(10):1127–1131. doi: 10.1136/jcp.38.10.1127. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Graham D. Y. Bile acid therapy for Helicobacter pylori. Aliment Pharmacol Ther. 1992 Oct;6(5):653–653. [PubMed] [Google Scholar]
- Graham D. Y. Campylobacter pylori and peptic ulcer disease. Gastroenterology. 1989 Feb;96(2 Pt 2 Suppl):615–625. doi: 10.1016/s0016-5085(89)80057-5. [DOI] [PubMed] [Google Scholar]
- Graham D. Y., Malaty H. M., Evans D. G., Evans D. J., Jr, Klein P. D., Adam E. Epidemiology of Helicobacter pylori in an asymptomatic population in the United States. Effect of age, race, and socioeconomic status. Gastroenterology. 1991 Jun;100(6):1495–1501. doi: 10.1016/0016-5085(91)90644-z. [DOI] [PubMed] [Google Scholar]
- Hoare A. M., McLeish A., Thompson H., Alexander-Williams J. Selection of patients for bile diversion surgery: use of bile acid measurement in fasting gastric aspirates. Gut. 1978 Mar;19(3):163–165. doi: 10.1136/gut.19.3.163. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jones D. M., Eldridge J., Fox A. J., Sethi P., Whorwell P. J. Antibody to the gastric campylobacter-like organism ("Campylobacter pyloridis")--clinical correlations and distribution in the normal population. J Med Microbiol. 1986 Aug;22(1):57–62. doi: 10.1099/00222615-22-1-57. [DOI] [PubMed] [Google Scholar]
- Karttunen T., Niemelä S. Campylobacter pylori and duodenogastric reflux in peptic ulcer disease and gastritis. Lancet. 1988 Jan 16;1(8577):118–118. doi: 10.1016/s0140-6736(88)90314-5. [DOI] [PubMed] [Google Scholar]
- Katelaris P. H., Tippett G. H., Norbu P., Lowe D. G., Brennan R., Farthing M. J. Dyspepsia, Helicobacter pylori, and peptic ulcer in a randomly selected population in India. Gut. 1992 Nov;33(11):1462–1466. doi: 10.1136/gut.33.11.1462. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lasson A. The postcholecystectomy syndrome: diagnostic and therapeutic strategy. Scand J Gastroenterol. 1987 Oct;22(8):897–902. doi: 10.3109/00365528708991932. [DOI] [PubMed] [Google Scholar]
- Latif A. H., Shami S. K., Batchoun R., Murad N., Sartawi O. Helicobacter pylori: a Jordanian study. Postgrad Med J. 1991 Nov;67(793):994–998. doi: 10.1136/pgmj.67.793.994. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Marshall B. J., McGechie D. B., Rogers P. A., Glancy R. J. Pyloric Campylobacter infection and gastroduodenal disease. Med J Aust. 1985 Apr 15;142(8):439–444. doi: 10.5694/j.1326-5377.1985.tb113444.x. [DOI] [PubMed] [Google Scholar]
- Marshall B. J., Warren J. R. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984 Jun 16;1(8390):1311–1315. doi: 10.1016/s0140-6736(84)91816-6. [DOI] [PubMed] [Google Scholar]
- Meshkinpour H., Marks J. W., Schoenfield L. J., Bonnoris G. G., Carter S. Reflux gastritis syndrome: mechanism of symptoms. Gastroenterology. 1980 Dec;79(6):1283–1287. [PubMed] [Google Scholar]
- Nicolai J. J., Speelman P., Tytgat G. N., van der Stadt J. Comparison of the combination of cholestyramine/alginates with placebo in the treatment of postgastrectomy biliary reflux gastritis. Eur J Clin Pharmacol. 1981;21(3):189–194. doi: 10.1007/BF00627919. [DOI] [PubMed] [Google Scholar]
- O'Connor H. J., Dixon M. F., Wyatt J. I., Axon A. T., Ward D. C., Dewar E. P., Johnston D. Effect of duodenal ulcer surgery and enterogastric reflux on Campylobacter pyloridis. Lancet. 1986 Nov 22;2(8517):1178–1181. doi: 10.1016/s0140-6736(86)92193-8. [DOI] [PubMed] [Google Scholar]
- Paul A., Troidl H., Gay K., Viell B., Bode C. Dyspepsie und Nahrungsmittelunverträglichkeiten beim symptomatischen Gallensteinleiden. Hilft die Cholecystektomie? Chirurg. 1991 Jun;62(6):462–466. [PubMed] [Google Scholar]
- Pettross C. W., Appleman M. D., Cohen H., Valenzuela J. E., Chandrasoma P., Laine L. A. Prevalence of Campylobacter pylori and association with antral mucosal histology in subjects with and without upper gastrointestinal symptoms. Dig Dis Sci. 1988 Jun;33(6):649–653. doi: 10.1007/BF01540425. [DOI] [PubMed] [Google Scholar]
- Price A. B., Levi J., Dolby J. M., Dunscombe P. L., Smith A., Clark J., Stephenson M. L. Campylobacter pyloridis in peptic ulcer disease: microbiology, pathology, and scanning electron microscopy. Gut. 1985 Nov;26(11):1183–1188. doi: 10.1136/gut.26.11.1183. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rashed R. S., Ayoola E. A., Mofleh I. A., Chowdhury M. N., Mahmood K., Faleh F. Z. Helicobacter pylori and dyspepsia in an Arab population. Trop Geogr Med. 1992 Oct;44(4):304–307. [PubMed] [Google Scholar]
- Rauws E. A., Langenberg W., Houthoff H. J., Zanen H. C., Tytgat G. N. Campylobacter pyloridis-associated chronic active antral gastritis. A prospective study of its prevalence and the effects of antibacterial and antiulcer treatment. Gastroenterology. 1988 Jan;94(1):33–40. [PubMed] [Google Scholar]
- Ritchie W. P., Jr Acute gastric mucosal damage induced by bile salts, acid, and ischemia. Gastroenterology. 1975 Apr;68(4 Pt 1):699–707. [PubMed] [Google Scholar]
- Ritchie W. P., Jr Alkaline reflux gastritis. An objective assessment of its diagnosis and treatment. Ann Surg. 1980 Sep;192(3):288–298. doi: 10.1097/00000658-198009000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Robles-Campos R., Lujan-Mompean J. A., Parrilla-Paricio P., Bermejo-Lopez J., Liron-Ruiz R., Torralba-Martinez J. A., Morales-Cuenca G., Molina-Martinzez J. A. Role of Helicobacter pylori infection and duodenogastric reflux in the pathogenesis of alkaline reflux gastritis after gastric operations. Surg Gynecol Obstet. 1993 Jun;176(6):594–598. [PubMed] [Google Scholar]
- Ros E., Zambon D. Postcholecystectomy symptoms. A prospective study of gall stone patients before and two years after surgery. Gut. 1987 Nov;28(11):1500–1504. doi: 10.1136/gut.28.11.1500. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Skinner J. M., Heenan P. J., Whitehead R. Atrophic gastritis in gastrectomy specimens. Br J Surg. 1975 Jan;62(1):23–25. doi: 10.1002/bjs.1800620107. [DOI] [PubMed] [Google Scholar]
- Sobala G. M., O'Connor H. J., Dewar E. P., King R. F., Axon A. T., Dixon M. F. Bile reflux and intestinal metaplasia in gastric mucosa. J Clin Pathol. 1993 Mar;46(3):235–240. doi: 10.1136/jcp.46.3.235. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Steer H. W. The gastro-duodenal epithelium in peptic ulceration. J Pathol. 1985 Aug;146(4):355–362. doi: 10.1002/path.1711460409. [DOI] [PubMed] [Google Scholar]
- Stein H. J., Smyrk T. C., DeMeester T. R., Rouse J., Hinder R. A. Clinical value of endoscopy and histology in the diagnosis of duodenogastric reflux disease. Surgery. 1992 Oct;112(4):796–804. [PubMed] [Google Scholar]
- Tompkins D. S., West A. P. Campylobacter pylori, acid, and bile. J Clin Pathol. 1987 Nov;40(11):1387–1387. doi: 10.1136/jcp.40.11.1387-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wyatt J. I., Rathbone B. J., Heatley R. V. Local immune response to gastric Campylobacter in non-ulcer dyspepsia. J Clin Pathol. 1986 Aug;39(8):863–870. doi: 10.1136/jcp.39.8.863. [DOI] [PMC free article] [PubMed] [Google Scholar]