Skip to main content
PMC home page
Gut logoLink to Gut
. 1995 Nov;37(5):595–597. doi: 10.1136/gut.37.5.595

Peptides and gastrointestinal mucosal integrity.

R J Playford 1
PMCID: PMC1382859  PMID: 8549930

Full text

PDF
595

Images in this article

595Figure 1
on p.595
596Figure 2
on p.596

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alison M. R., Chinery R., Poulsom R., Ashwood P., Longcroft J. M., Wright N. A. Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor and transforming growth factor alpha mRNAs in rat stomach. J Pathol. 1995 Apr;175(4):405–414. doi: 10.1002/path.1711750408. [DOI] [PubMed] [Google Scholar]
  2. Cartlidge S. A., Elder J. B. Transforming growth factor alpha and epidermal growth factor levels in normal human gastrointestinal mucosa. Br J Cancer. 1989 Nov;60(5):657–660. doi: 10.1038/bjc.1989.334. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Corfield A. P., Williams A. J., Clamp J. R., Wagner S. A., Mountford R. A. Degradation by bacterial enzymes of colonic mucus from normal subjects and patients with inflammatory bowel disease: the role of sialic acid metabolism and the detection of a novel O-acetylsialic acid esterase. Clin Sci (Lond) 1988 Jan;74(1):71–78. doi: 10.1042/cs0740071. [DOI] [PubMed] [Google Scholar]
  4. Dignass A. U., Podolsky D. K. Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor beta. Gastroenterology. 1993 Nov;105(5):1323–1332. doi: 10.1016/0016-5085(93)90136-z. [DOI] [PubMed] [Google Scholar]
  5. Dignass A., Lynch-Devaney K., Kindon H., Thim L., Podolsky D. K. Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway. J Clin Invest. 1994 Jul;94(1):376–383. doi: 10.1172/JCI117332. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Freeman T. C., Curry B. J., Calam J., Woodburn J. R. Pancreatic secretory trypsin inhibitor stimulates the growth of rat pancreatic carcinoma cells. Gastroenterology. 1990 Nov;99(5):1414–1420. doi: 10.1016/0016-5085(90)91170-b. [DOI] [PubMed] [Google Scholar]
  7. Fukuoka S., Fushiki T., Kitagawa Y., Sugimoto E., Iwai K. Competition of a growth stimulating-/cholecystokinin (CCK) releasing-peptide (monitor peptide) with epidermal growth factor for binding to 3T3 fibroblasts. Biochem Biophys Res Commun. 1987 Jun 15;145(2):646–650. doi: 10.1016/0006-291x(87)91013-8. [DOI] [PubMed] [Google Scholar]
  8. Itoh M., Imai S., Joh T., Yokoyama Y., Yasue N., Iwai A., Matsusako K., Endoh K., Kawai T., Takeuchi T. Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat. J Clin Gastroenterol. 1990;12 (Suppl 1):S187–S191. doi: 10.1097/00004836-199001001-00030. [DOI] [PubMed] [Google Scholar]
  9. Nunez A. M., Berry M., Imler J. L., Chambon P. The 5' flanking region of the pS2 gene contains a complex enhancer region responsive to oestrogens, epidermal growth factor, a tumour promoter (TPA), the c-Ha-ras oncoprotein and the c-jun protein. EMBO J. 1989 Mar;8(3):823–829. doi: 10.1002/j.1460-2075.1989.tb03443.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Olsen P. S., Poulsen S. S., Therkelsen K., Nexø E. Effect of sialoadenectomy and synthetic human urogastrone on healing of chronic gastric ulcers in rats. Gut. 1986 Dec;27(12):1443–1449. doi: 10.1136/gut.27.12.1443. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Playford R. J., Batten J. J., Freeman T. C., Beardshall K., Vesey D. A., Fenn G. C., Baron J. H., Calam J. Gastric output of pancreatic secretory trypsin inhibitor is increased by misoprostol. Gut. 1991 Nov;32(11):1396–1400. doi: 10.1136/gut.32.11.1396. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Playford R. J., Hanby A. M., Quinn C., Calam J. Influence of inflammation and atrophy on pancreatic secretory trypsin inhibitor levels within the gastric mucosa. Gastroenterology. 1994 Mar;106(3):735–741. doi: 10.1016/0016-5085(94)90709-9. [DOI] [PubMed] [Google Scholar]
  13. Playford R. J., Marchbank T., Calnan D. P., Calam J., Royston P., Batten J. J., Hansen H. F. Epidermal growth factor is digested to smaller, less active forms in acidic gastric juice. Gastroenterology. 1995 Jan;108(1):92–101. doi: 10.1016/0016-5085(95)90012-8. [DOI] [PubMed] [Google Scholar]
  14. Playford R. J., Marchbank T., Chinery R., Evison R., Pignatelli M., Boulton R. A., Thim L., Hanby A. M. Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration. Gastroenterology. 1995 Jan;108(1):108–116. doi: 10.1016/0016-5085(95)90014-4. [DOI] [PubMed] [Google Scholar]
  15. Playford R. J., Woodman A. C., Clark P., Watanapa P., Vesey D., Deprez P. H., Williamson R. C., Calam J. Effect of luminal growth factor preservation on intestinal growth. Lancet. 1993 Apr 3;341(8849):843–848. doi: 10.1016/0140-6736(93)93057-8. [DOI] [PubMed] [Google Scholar]
  16. Poulsom R., Wright N. A. Trefoil peptides: a newly recognized family of epithelial mucin-associated molecules. Am J Physiol. 1993 Aug;265(2 Pt 1):G205–G213. doi: 10.1152/ajpgi.1993.265.2.G205. [DOI] [PubMed] [Google Scholar]
  17. Romano M., Polk W. H., Awad J. A., Arteaga C. L., Nanney L. B., Wargovich M. J., Kraus E. R., Boland C. R., Coffey R. J. Transforming growth factor alpha protection against drug-induced injury to the rat gastric mucosa in vivo. J Clin Invest. 1992 Dec;90(6):2409–2421. doi: 10.1172/JCI116132. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Svanes K., Ito S., Takeuchi K., Silen W. Restitution of the surface epithelium of the in vitro frog gastric mucosa after damage with hyperosmolar sodium chloride. Morphologic and physiologic characteristics. Gastroenterology. 1982 Jun;82(6):1409–1426. [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES