Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in C. elegans

Abstract

Correction to: The EMBO Journal (2005) 24, 2613–2623. doi:10.1038/sj.emboj.7600726

The authors have discovered an error in the above article.

In our original paper, we inadvertently left out references for the ‘Essential gene' column of Table I. Please find below the corrected version. We have now split this column into ‘Lethal mutant' and ‘Lethal by RNAi' columns and added citations. We apologize to authors who were not cited in the original paper and for any inconvenience caused.

Table 1.

New and previously studied synMuv genes

Predicted gene	Locus	Human homologue	Brief description	Found in screen	Lethal mutant	Lethal by RNAi	Previously known
C03B8.4	lin-13/lin-51	ZFP28 (3.4E−18)	Zinc-finger protein	ND	Yesa,b	No	Yesa,b
C32F10.2	lin-35	RBL2 (1E–46)	Retinoblastoma-like	B	Noc	No	Yesc
C47D12.1	trr-1	TRRAP (1.7E–266)	TRRAP protein	B	Yesd	Yes	Yesd
C53A5.3	hda-1/gon-10	HDAC1 (1.7E–170)	Histone deacetylase 1	B	Yese	Yes	Yesc
F26F12.7	let-418	Mi-2 beta (0.0)	Chromodomain helicase protein	ND*	Yesf	Yesf,l	Yesf,l
F26G5.9	tam-1	TRIM9 (7.9E–14)	RING finger/B-Box protein	No	Nog	No	Yesg
F44B9.6	lin-36	None	None	B	Noa,h	No	Yesa,h
JC8.6	—	MTL5 (3.1E–42)	Tesmin	B	ND	No	Yest
K01G5.2	hpl-2	CBX1 (1.6E–21)	Chromobox protein	No	Yesi	Yes	Yesi
K07A1.12	lin-53/rba-2	RBBP4 (1.8E–171)	Rb-associated protein 48	B	Noc	Yes	Yesc
M04B2.1	mep-1/gei-2	ZNF406 (7E–04)	Zinc-finger protein	B	Yesj	Yes	Yesj
T23G7.1	dpl-1	TFDP1 (4.1E–64)	Transcription factor DP-1	ND*	Yesd,k	Yesd,k	Yesd,k
T27C4.4	egr-1	MTA1L1 (4E–66)	Metastasis-associated protein	A	Yesl,m	Yes	Yesl,m
VC5.4	mys-1	HTATIP (3.5E–121)	TIP60 histone acetyltransferase	No	Yesd	Yes	Yesd
Y102A5C.18	efl-1	E2F4 (9.2E–41)	Transcription factor E2F4	B	Yesd,k	Yes	Yesd,k
ZK632.13	lin-52	LOC91750 (2.3E–06)	Novel protein	B	Yesn	No	Yesn
ZK637.7	lin-9	TGS (1.3E–67)	Tudor domain	B	Yesa,o	No	Yesa,o
ZK662.4	lin-15b	None	None	ND	Nop,q,r	No	Yesp,q,r
ZK678.1	lin-15a	None	None	ND	Nop,q,r	No	Yesp,q,r
E01A2.4	—	NKAP (8.3E–50)	Nuclear NF-κB activ. protein	B	ND	Yes	No
F29B9.6	ubc-9	UBE2I (2.3E–70)	Ubc9/SUMO-1 conj. enzyme	No	ND	Yes	No
K12C11.2	smo-1	UBL1 (2.5E–25)	SUMO	A, B	Yess	Yes	No
R05D3.11	met-2	SETDB1 (5.3E–44)	Histone H3 lysine-9 methyltransferase	B	ND	No	Nou
R06C7.7	rls-1/lin-61	L3MBTL2 (2E–42)	Lethal (3) malignant brain tumor	B	ND	Yes	Nov
W01G7.3	—	POLR2J (1.6E–37)	RNA pol II (13.3 kDa)	B	ND	Yes	No
W02A11.4	uba-2	UBE1 (2.4E–107)	Uba2/SUMO activating enzyme subunit 2	A, B	ND	Yes	No
W07B3.2	gei-4	CALD1 (1.2E–10)	Unknown	B	ND	Yes	No
Y71G12B.9	—	ACRC (2E–13)	Unknown	B	ND	No	No
Shown are the predicted gene name, locus, closest human homologue with BlastP E-value in parentheses, a brief description of the protein, whether the gene was identified in the lin-15A screen (designated ‘B'), the lin-15B screen (designated ‘A') or not screened (designated ‘ND' for clones not in the library or ‘ND*' for RNAi clones found to be incorrect upon sequencing), if a mutant is lethal (designated ND if no mutant is published), if the gene shows a lethal RNAi phenotype (defined as embryonic lethal, larval lethal, or sterile) in our experiments except where referenced, and if it is a previously known synMuv gene.
aFerguson and Horvitz (1989).
bMelendez and Greenwald (2000) (lin-13 null mutant is temperature sensitive and only inviable at 25°C).
cLu and Horvitz (1998) (Hn-53 mutant allele is not null).
dCeol and Horvitz (2004).
eDufourcq et al (2002).
fvon Zelewsky et al (2000).
gHsieh et al (1999).
hThomas and Horvitz (1999).
iCouteau et al (2002).
jUnhavaithaya et al (2002).
kPage et al (2001).
lSolari and Ahringer (2000).
mChen and Han (2001).
nThomas et al (2003).
oBeitel et al (2000).
pFerguson and Horvitz (1985).
qClark et al (1994).
rHuang et al (1994).
sBroday et al (2004).
tOwen et al (2003).
uIndependently identified as a synMuv gene by E Andersen and B Horvitz (personal communication).
vIndependently identified as a synMuv gene by X Lu, M Harrison and B Horvitz (personal communication).