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. 2002 Jun;12(6):1012.
PMCID: PMC1383738

Genome Research 12: 527–530 (2002)

Functional Diversity of Mx Proteins: Variations on a Theme of Host Resistance to Infection

Seung-Hwan Lee and Silvia M. Vidal

In the reproduction of Table 1. Intracellular Localization and Antiviral Spectrum for Selected MX Proteins, the first column (Species) was truncated. The corrected table has been reprinted in its entirety here.

Table 1.

Intracellular Localization and Antiviral Spectrum for Selected Mx Proteins

Species Gene Accession no. Size (aa) Intracellular localization Antiviral specificity






Virus Family


Human MxA P20591 661 Cytoplasm Influenza virus, Thogoto virus Orthomyxoviridae1
Vesicular stomatitis virus Rhabdoviridae2
Measles virus Paramyxoviridae3
Hantaan virus Bunyaviridae4
Coxsackievirus B4 Picornaviridae5
Semliki Forest virus Togaviridae6
MxB P20592 715 Nucleus and cytoplasm Inactive
Mouse Mx1 P09922 631 Nucleus Influenza virus, Thogoto virus, Dhori virus Orthomyxoviridae1
Mx2 NP_38634 655 Cytoplasm Vesicular stomatitis virus Rhabdoviridae2
Hantaan virus Bunyaviridae4
Rat Mx1 P18588 652 Nucleus Influenza virus, Thogoto virus Orthomyxoviridae1
Mx2 P18589 659 Cytoplasm Vesicular stomatitis virus Rhabdoviridae2
LaCrosse virus, Rift Valley fever virus Bunyaviridae4
Mx3 P18590 659 Cytoplasm Inactive
Chicken Mx Q92597 705 Cytoplasm Influenza virus Orthomyxoviridae1
Vesicular stomatitis virus Rhabdoviridae2
Duck Mx P33238 721 Nucleus and cytoplasm Inactive

1,4Enveloped, negative-sense segmented RNA virus 

2,3Enveloped, negative-sense non-segmented RNA virus 

5

Naked, positive-sense non-segmented RNA virus 

6

Enveloped, positive-sense, non-segmented RNA virus 

We apologize for any confusion this may have caused.


Articles from Genome Research are provided here courtesy of Cold Spring Harbor Laboratory Press

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