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. 1990 Jul;70(3):411–413.

In vivo IL-1 potentiates both specific and non-specific arms of immune response to infection.

C Cheers 1, Y F Zhan 1, P J Egan 1
PMCID: PMC1384174  PMID: 2379944

Abstract

Injection of 10(5) U interleukin-1 (IL-1) 4 hr before intravenous infection with Listeria monocytogenes hastens recovery of mice. This is accompanied not only by early stimulation of colony-forming cells in the spleen to levels higher than those in untreated, infected mice but also by accelerated activation of lymphokine-producing, specific T lymphocytes.

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Selected References

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