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. 1990 Jun;70(2):247–250.

T cells do not mediate the initial suppression of a Salmonella infection in the RES.

C E Hormaeche 1, P Mastroeni 1, A Arena 1, J Uddin 1, H S Joysey 1
PMCID: PMC1384201  PMID: 2197215

Abstract

The course of a sublethal salmonella infection was followed in mice rendered susceptible by irradiation, reconstituted with T-cell-depleted bone marrow from normal donors and given a synergistic pool of CD4 and CD8 monoclonal antibodies. The results indicate that the host response causing the early plateau and suppression of bacterial growth at the end of the first week of the infection, which is essential for survival, does not require T cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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