Abstract
The results of this study show that acquired protective immunity to Listeria monocytogenes, measured as the capacity of splenic T cells to passively transfer acquired resistance to normal syngeneic recipients, was mediated by a population of cyclophosphamide-sensitive CD4- CD8+ T cells. The results further show, in contrast, that memory immunity to listeriosis, which was defined as resistance transferred by T cells harvested from infected animals that had received ampicillin chemotherapy, was shown to be mediated by cyclophosphamide-resistant CD4+ CD8- T cells.
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Selected References
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