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. 1989 Dec;68(4):474–478.

The polymeric immunoglobulin A receptor is present on hepatocytes in human liver.

J H Perez 1, D G Wight 1, J I Wyatt 1, M Van Schaik 1, B M Mullock 1, J P Luzio 1
PMCID: PMC1385533  PMID: 2606507

Abstract

A monoclonal antibody raised against human colostrum secretory component produced even staining of hepatocyte plasma membranes, as well as bile duct lining cells, in all sections examined from eight normal and three abnormal human livers. Human bile samples incubated with free secretory component degraded it to varying extents, probably proteolytically; true levels of free secretory component will therefore often be higher than those reported. It seems likely that human liver resembles that of other mammals in transferring polymeric IgA through hepatocytes to the bile by means of the polymeric IgA receptor.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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