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. 1987 Nov;24(5):621–625. doi: 10.1111/j.1365-2125.1987.tb03221.x

Inter-relationship among individual vitamin K-dependent clotting factors at different levels of anticoagulation.

E Chan 1, L Aarons 1, M Serlin 1, A Breckenridge 1, M Rowland 1
PMCID: PMC1386334  PMID: 3435692

Abstract

1. The effect of subtherapeutic doses of warfarin on the activities of the four vitamin K-dependent clotting factors was studied at steady state in five patients each of whom had completed a therapeutic course of anticoagulation. 2. The four clotting factor activities were shown to be depressed to a similar extent for a given dose of warfarin. 3. The prothrombin complex activity was significantly lower than that of any of the clotting factors.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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