Skip to main content
PMC home page
British Journal of Clinical Pharmacology logoLink to British Journal of Clinical Pharmacology
. 1988 Mar;25(3):283–287. doi: 10.1111/j.1365-2125.1988.tb03305.x

Adverse reactions to the non-drug constituents of nebuliser solutions.

R Beasley 1, P Rafferty 1, S T Holgate 1
PMCID: PMC1386351  PMID: 3358893

Full text

PDF
283

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allegra L., Bianco S. Non-specific broncho-reactivity obtained with an ultrasonic aerosol of distilled water. Eur J Respir Dis Suppl. 1980;106:41–49. [PubMed] [Google Scholar]
  2. Anderson S. D., Schoeffel R. E., Finney M. Evaluation of ultrasonically nebulised solutions for provocation testing in patients with asthma. Thorax. 1983 Apr;38(4):284–291. doi: 10.1136/thx.38.4.284. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Barnes K. L., Clifford R., Holgate S. T., Murphy D., Comber P., Bell E. Bacterial contamination of home nebuliser. Br Med J (Clin Res Ed) 1987 Oct 3;295(6602):812–812. doi: 10.1136/bmj.295.6602.812. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Beasley C. R., Rafferty P., Holgate S. T. Bronchoconstrictor properties of preservatives in ipratropium bromide (Atrovent) nebuliser solution. Br Med J (Clin Res Ed) 1987 May 9;294(6581):1197–1198. doi: 10.1136/bmj.294.6581.1197-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Clark R. J. Exacerbation of asthma after nebulised beclomethasone diproprionate. Lancet. 1986 Sep 6;2(8506):574–575. doi: 10.1016/s0140-6736(86)90140-6. [DOI] [PubMed] [Google Scholar]
  6. Cockcroft D. W., Berscheid B. A. Effect of pH on bronchial response to inhaled histamine. Thorax. 1982 Feb;37(2):133–136. doi: 10.1136/thx.37.2.133. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Connolly C. K. Adverse reaction to ipratropium bromide. Br Med J (Clin Res Ed) 1982 Oct 2;285(6346):934–935. doi: 10.1136/bmj.285.6346.934. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Downes H., Hirshman C. A. Calcium chelators increase airway responsiveness. J Appl Physiol (1985) 1985 Jul;59(1):92–95. doi: 10.1152/jappl.1985.59.1.92. [DOI] [PubMed] [Google Scholar]
  9. Downes H., Hirshman C. A. Importance of calcium in citric acid-induced airway constriction. J Appl Physiol Respir Environ Exerc Physiol. 1983 Nov;55(5):1496–1500. doi: 10.1152/jappl.1983.55.5.1496. [DOI] [PubMed] [Google Scholar]
  10. Edmondson E. B., Reinarz J. A., Pierce A. K., Sanford J. P. Nebulization equipment. A potential source of infection in gram-negative pneumonias. Am J Dis Child. 1966 Apr;111(4):357–360. doi: 10.1001/archpedi.1966.02090070055004. [DOI] [PubMed] [Google Scholar]
  11. Eschenbacher W. L., Boushey H. A., Sheppard D. Alteration in osmolarity of inhaled aerosols cause bronchoconstriction and cough, but absence of a permeant anion causes cough alone. Am Rev Respir Dis. 1984 Feb;129(2):211–215. [PubMed] [Google Scholar]
  12. Fine J. M., Gordon T., Thompson J. E., Sheppard D. The role of titratable acidity in acid aerosol-induced bronchoconstriction. Am Rev Respir Dis. 1987 Apr;135(4):826–830. doi: 10.1164/arrd.1987.135.4.826. [DOI] [PubMed] [Google Scholar]
  13. Jolobe O. M. Adverse reaction to ipratropium bromide. Br Med J (Clin Res Ed) 1982 Nov 13;285(6352):1425–1426. doi: 10.1136/bmj.285.6352.1425-d. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Jones P. D., Moritz V., Pierce R. J. Microbial contamination of domiciliary nebuliser therapy equipment. Aust N Z J Med. 1985 Oct;15(5):585–589. [PubMed] [Google Scholar]
  15. Koenig J. Q., Pierson W. E., Horike M. The effects of inhaled sulfuric acid on pulmonary function in adolescent asthmatics. Am Rev Respir Dis. 1983 Aug;128(2):221–225. doi: 10.1164/arrd.1983.128.2.221. [DOI] [PubMed] [Google Scholar]
  16. Koepke J. W., Selner J. C., Dunhill A. L. Presence of sulfur dioxide in commonly used bronchodilator solutions. J Allergy Clin Immunol. 1983 Nov;72(5 Pt 1):504–508. doi: 10.1016/0091-6749(83)90588-2. [DOI] [PubMed] [Google Scholar]
  17. Kuhn R. J., Lubin A. H., Jones P. R., Nahata M. C. Bacterial contamination of aerosol solutions used to treat cystic fibrosis. Am J Hosp Pharm. 1982 Feb;39(2):308–309. [PubMed] [Google Scholar]
  18. Lilker E. S., Jauregui R. Airway response to water inhalation: a new test for "bronchial reactivity". N Engl J Med. 1981 Sep 17;305(12):702–702. doi: 10.1056/NEJM198109173051221. [DOI] [PubMed] [Google Scholar]
  19. Mann J. S., Howarth P. H., Holgate S. T. Bronchoconstriction induced by ipratropium bromide in asthma: relation to hypotonicity. Br Med J (Clin Res Ed) 1984 Aug 25;289(6443):469–469. doi: 10.1136/bmj.289.6443.469. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Mertz J. J., Scharer L., McClement J. H. A hospital outbreak of Klebsiella pneumonia from inhalation therapy with contaminated aerosol solutions. Am Rev Respir Dis. 1967 Mar;95(3):454–460. doi: 10.1164/arrd.1967.95.3.454. [DOI] [PubMed] [Google Scholar]
  21. Miszkiel K. A., Beasley R., Rafferty P., Holgate S. T. The contribution of histamine release to bronchoconstriction provoked by inhaled benzalkonium chloride in asthma. Br J Clin Pharmacol. 1988 Feb;25(2):157–163. doi: 10.1111/j.1365-2125.1988.tb03286.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Morris A. H. Nebulizer contamination in a burn unit. Am Rev Respir Dis. 1973 May;107(5):802–808. doi: 10.1164/arrd.1973.107.5.802. [DOI] [PubMed] [Google Scholar]
  23. O'Callaghan C., Milner A. D., Swarbrick A. Paradoxical deterioration in lung function after nebulised salbutamol in wheezy infants. Lancet. 1986 Dec 20;2(8521-22):1424–1425. doi: 10.1016/s0140-6736(86)92735-2. [DOI] [PubMed] [Google Scholar]
  24. Prendiville A., Green S., Silverman M. Paradoxical response to nebulised salbutamol in wheezy infants, assessed by partial expiratory flow-volume curves. Thorax. 1987 Feb;42(2):86–91. doi: 10.1136/thx.42.2.86. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. REINARZ J. A., PIERCE A. K., MAYS B. B., SANFORD J. P. THE POTENTIAL ROLE OF INHALATION THERAPY EQUIPMENT IN NOSOCOMIAL PULMONARY INFECTION. J Clin Invest. 1965 May;44:831–839. doi: 10.1172/JCI105195. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Reisman R. E. Asthma induced by adrenergic aerosols. J Allergy. 1970 Sep;46(3):162–177. doi: 10.1016/0021-8707(70)90095-x. [DOI] [PubMed] [Google Scholar]
  27. Sanders C. V., Jr, Luby J. P., Johanson W. G., Jr, Barnett J. A., Sanford J. P. Serratia marcescens infections from inhalation therapy medications: nosocomial outbreak. Ann Intern Med. 1970 Jul;73(1):15–21. doi: 10.7326/0003-4819-73-1-15. [DOI] [PubMed] [Google Scholar]
  28. Schwartz H. J., Chester E. H. Bronchospastic responses to aerosolized metabisulfite in asthmatic subjects: potential mechanisms and clinical implications. J Allergy Clin Immunol. 1984 Oct;74(4 Pt 1):511–513. doi: 10.1016/0091-6749(84)90387-7. [DOI] [PubMed] [Google Scholar]
  29. Sheppard D., Rizk N. W., Boushey H. A., Bethel R. A. Mechanism of cough and bronchoconstriction induced by distilled water aerosol. Am Rev Respir Dis. 1983 Jun;127(6):691–694. doi: 10.1164/arrd.1983.127.6.691. [DOI] [PubMed] [Google Scholar]
  30. Sheppard D., Saisho A., Nadel J. A., Boushey H. A. Exercise increases sulfur dioxide-induced bronchoconstriction in asthmatic subjects. Am Rev Respir Dis. 1981 May;123(5):486–491. doi: 10.1164/arrd.1981.123.5.486. [DOI] [PubMed] [Google Scholar]
  31. Sheppard D., Wong W. S., Uehara C. F., Nadel J. A., Boushey H. A. Lower threshold and greater bronchomotor responsiveness of asthmatic subjects to sulfur dioxide. Am Rev Respir Dis. 1980 Dec;122(6):873–878. doi: 10.1164/arrd.1980.122.6.873. [DOI] [PubMed] [Google Scholar]
  32. Smith C. M., Anderson S. D. Hyperosmolarity as the stimulus to asthma induced by hyperventilation? J Allergy Clin Immunol. 1986 May;77(5):729–736. doi: 10.1016/0091-6749(86)90419-7. [DOI] [PubMed] [Google Scholar]
  33. Trautlein J., Allegra J., Field J., Gillin M. Paradoxic bronchospasm after inhalation of isoptroterenol. Chest. 1976 Dec;70(6):711–714. doi: 10.1378/chest.70.6.711. [DOI] [PubMed] [Google Scholar]
  34. Twarog F. J., Leung D. Y. Anaphylaxis to a component of isoetharine (sodium bisulfite). JAMA. 1982 Oct 22;248(16):2030–2031. [PubMed] [Google Scholar]
  35. Utell M. J., Morrow P. E., Speers D. M., Darling J., Hyde R. W. Airway responses to sulfate and sulfuric acid aerosols in asthmatics. An exposure-response relationship. Am Rev Respir Dis. 1983 Sep;128(3):444–450. doi: 10.1164/arrd.1983.128.3.444. [DOI] [PubMed] [Google Scholar]
  36. Witek T. J., Jr, Schachter E. N. Detection of sulfur dioxide in bronchodilator aerosols. Chest. 1984 Oct;86(4):592–594. doi: 10.1378/chest.86.4.592. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Clinical Pharmacology are provided here courtesy of British Pharmacological Society

RESOURCES