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. 1969 Sep;170(3):369–384. doi: 10.1097/00000658-196909010-00006

The natural history and management of radiation induced injury of the gastrointestinal tract.

J J DeCosse, R S Rhodes, W B Wentz, J W Reagan, H J Dworken, W D Holden
PMCID: PMC1387682  PMID: 4979653

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ASHBAUGH D. G., OWENS J. C. Intestinal complications following irradiation for gynecologic cancer. Arch Surg. 1963 Jul;87:100–107. doi: 10.1001/archsurg.1963.01310130102013. [DOI] [PubMed] [Google Scholar]
  2. BARBER H. R., BRUNSCHWIG A. PELVIC EXENTERATION FOR EXTENSIVE VISCERAL NECROSIS FOLLOWING RADIATION THERAPY FOR GYNECOLOGIC CANCER. Obstet Gynecol. 1965 Apr;25:575–578. [PubMed] [Google Scholar]
  3. BLACK W. C., 3rd, ACKERMAN L. V. CARCINOMA OF THE LARGE INTESTINE AS A LATE COMPLICATION OF PELVIC RADIOTHERAPY. Clin Radiol. 1965 Jul;16:278–281. doi: 10.1016/s0009-9260(65)80059-9. [DOI] [PubMed] [Google Scholar]
  4. BRICK I. B. Effects of million volt irradiation on the gastrointestinal tract. AMA Arch Intern Med. 1955 Jul;96(1):26–31. doi: 10.1001/archinte.1955.04430010040004. [DOI] [PubMed] [Google Scholar]
  5. COLCOCK B. P., HUME A. Radiation injury to the sigmoid and rectum. Surg Gynecol Obstet. 1959 Mar;108(3):306–312. [PubMed] [Google Scholar]
  6. CONARD R. A. Effect of X-irradiation on intestinal motility of the rat. Am J Physiol. 1951 May;165(2):375–385. doi: 10.1152/ajplegacy.1951.165.2.375. [DOI] [PubMed] [Google Scholar]
  7. DRUCKER W. R., DAVIS J. H., HOLDEN W. D., REAGAN J. R. HEMORRHAGIC NECROSIS OF THE INTESTINE. A CLINICAL SYNDROME: PRESENCE WITHOUT ORGANIC VASCULAR OCCLUSION. Arch Surg. 1964 Jul;89:42–53. doi: 10.1001/archsurg.1964.01320010044006. [DOI] [PubMed] [Google Scholar]
  8. FABRIKANT J. I., ANLYAN W. G., CREADICK R. N. The management of radiation injuries to the intestines. South Med J. 1959 Oct;52:1186–1191. doi: 10.1097/00007611-195910000-00005. [DOI] [PubMed] [Google Scholar]
  9. FRANK R. C., POHLE E. A. Late radiation reaction in the small intestine manifest eight years after therapy; report of a case. Ann Surg. 1951 Jan;133(1):104–108. doi: 10.1097/00000658-195101000-00010. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. FRICK H. C., 2nd, TAYLOR H. C., Jr, GUTTMANN R. J., JACOX H. W., McKELWAY W. P. A study of complications in the surgical and radiation therapy of cancer of the cervix. Surg Gynecol Obstet. 1960 Oct;111:493–506. [PubMed] [Google Scholar]
  11. GARDNER C. E., Jr, ANLYAN W. G. Radiation injury to the small intestine; a report of one case of massive hemorrhage and one of perforation following therapy for carcinoma of the cervix. Surgery. 1952 May;31(5):746–749. [PubMed] [Google Scholar]
  12. GRAHAM J. B., VILLALBA R. J. Damage to the small intestine by radiotherapy. Surg Gynecol Obstet. 1963 Jun;116:665–668. [PubMed] [Google Scholar]
  13. GRAY M. J., KOTTMEIER H. L. Rectal and bladder injuries following radium therapy for carcinoma of the cervix at the Radium-hemmet. Am J Obstet Gynecol. 1957 Dec;74(6):1294–1303. doi: 10.1016/0002-9378(57)90017-0. [DOI] [PubMed] [Google Scholar]
  14. KAPLAN A. L., HUDGINS P. T., WALL J. A. POSTRADIATION PELVIC FIBROSIS SIMULATING RECURRENT CARCINOMA. Am J Obstet Gynecol. 1965 May 1;92:117–124. doi: 10.1016/0002-9378(65)90112-2. [DOI] [PubMed] [Google Scholar]
  15. KAPLAN B. J. Some clinical aspects of factitial proctitis; a report of 62 cases. Conn State Med J. 1956 May;20(5):357–363. [PubMed] [Google Scholar]
  16. KOTTMEIER H. L. COMPLICATIONS FOLLOWING RADIATION THERAPY IN CARCINOMA OF THE CERVIX AND THEIR TREATMENT. Am J Obstet Gynecol. 1964 Apr 1;88:854–866. doi: 10.1016/0002-9378(64)90733-1. [DOI] [PubMed] [Google Scholar]
  17. Lalanne C. M., Fajbisowicz S. Complications post-radiothérapiques dans le cancer du col utérin. Comparaison entre la radiothérapie classique et la télécobalthérapie associées à la curiethérapie intracavitaire. Ann Radiol (Paris) 1965;8(9):697–708. [PubMed] [Google Scholar]
  18. MACDONALD G. E., HOYT L. H. Corticotropin (ACTH) gel in treatment of irradiation enterocolitis; report of two cases. J Am Med Assoc. 1956 Aug 4;161(14):1381–1383. doi: 10.1001/jama.1956.62970140007009c. [DOI] [PubMed] [Google Scholar]
  19. Nance F. C., Persson A. V., Piker J. F. Radiation injuries to the lower gastrointestinal tract. Am Surg. 1968 Jan;34(1):21–25. [PubMed] [Google Scholar]
  20. PATH E. J., McCLURE J. N., Jr Intestinal obstruction; the protective action of sulfasuxidine and sulfathalidine to the ileum following vascular damage. Ann Surg. 1950 Feb;131(2):159-70, illust. doi: 10.1097/00000658-195002000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. PETERSON H. H., CLAUSEN E. G. Radiation injury to the small bowel with special consideration of surgical complications. Gastroenterology. 1956 Jul;31(1):47–55. [PubMed] [Google Scholar]
  22. POWEL-SMITH C. FACTORS INFLUENCING THE INCIDENCE OF RADIATION INJURY IN CANCER OF THE CERVIX. J Can Assoc Radiol. 1965 Jun;16:132–137. [PubMed] [Google Scholar]
  23. QUASTLER H. The nature of intestinal radiation death. Radiat Res. 1956 Apr;4(4):303–320. [PubMed] [Google Scholar]
  24. Quan S. H. Factitial proctitis due to irradiation for cancer of the cervix uteri. Surg Gynecol Obstet. 1968 Jan;126(1):70–74. [PubMed] [Google Scholar]
  25. REEVES R. J., CAVANAUGH P. J., SHARPE K. W., THORNE W. A., WINKLER C., SANDERS A. P. FAT ABSORPTION STUDIES AND SMALL BOWEL X-RAY STUDIES IN PATIENTS UNDERGOING CO-60 TELETHERAPY AND/OR RADIUM APPLICATION. Am J Roentgenol Radium Ther Nucl Med. 1965 Aug;94:848–851. [PubMed] [Google Scholar]
  26. REQUARTH W., ROBERTS S. Intestinal injuries following irradiation of pelvic viscera for malignancy. AMA Arch Surg. 1956 Oct;73(4):682–688. doi: 10.1001/archsurg.1956.01280040138016. [DOI] [PubMed] [Google Scholar]
  27. RUBIN P., RYPLANSKY A., DUTTON A. Incidence of pelvic malignancies following irradiation for benign gynecologic conditions. Am J Roentgenol Radium Ther Nucl Med. 1961 Mar;85:503–514. [PubMed] [Google Scholar]
  28. SHERMAN L. F. A reevaluation of the factitial proctitis problem. Am J Surg. 1954 Nov;88(5):773–779. doi: 10.1016/0002-9610(54)90274-3. [DOI] [PubMed] [Google Scholar]
  29. SLAUGHTER D. P., SOUTHWICK H. W. Mucosal carcinomas as a result of irradiation. AMA Arch Surg. 1957 Mar;74(3):420–429. doi: 10.1001/archsurg.1957.01280090118015. [DOI] [PubMed] [Google Scholar]
  30. SMITH J. Carcinoma of the rectum following irradiation of carcinoma of the cervix. Proc R Soc Med. 1962 Aug;55:701–702. [PMC free article] [PubMed] [Google Scholar]
  31. SUGG W. L., LAWLER W. H., ACKERMAN L. V., BUTCHER H. R., Jr Operative therapy for severe irradiational injury in the enteral and urinary tracts. Ann Surg. 1963 Jan;157:62–70. doi: 10.1097/00000658-196301000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Trier J. S., Browning T. H. Morphologic response of the mucosa of human small intestine to x-ray exposure. J Clin Invest. 1966 Feb;45(2):194–204. doi: 10.1172/JCI105332. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. WEINBREN K., FITSCHEN W., COHEN M. The unmasking by regeneration of latent irradiation effects in the rat liver. Br J Radiol. 1960 Jul;33:419–425. doi: 10.1259/0007-1285-33-391-419. [DOI] [PubMed] [Google Scholar]
  34. WENTZ W. B., LEWIS G. C., Jr CORRELATION OF HISTOLOGIC MORPHOLOGY AND SURVIVAL IN CERVICAL CANCER FOLLOWING RADIATION THERAPY. Obstet Gynecol. 1965 Aug;26:228–232. [PubMed] [Google Scholar]
  35. WENTZ W. B., REAGAN J. W. Survival in cervical cancer with respect to cell type. Cancer. 1959 Mar-Apr;12(2):384–388. doi: 10.1002/1097-0142(195903/04)12:2<384::aid-cncr2820120222>3.0.co;2-c. [DOI] [PubMed] [Google Scholar]
  36. WHITE W. C., FINN F. W. The late complications following irradiation of pelvic viscera. Am J Obstet Gynecol. 1951 Jul;62(1):65–74. doi: 10.1016/0002-9378(51)91091-5. [DOI] [PubMed] [Google Scholar]
  37. WILEY H. M., SUGARBAKER E. D. Roentgenotherapeutic changes in the small intestine; surgical aspects. Cancer. 1950 Jul;3(4):629–640. doi: 10.1002/1097-0142(1950)3:4<629::aid-cncr2820030408>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
  38. Warren S., Friedman N. B. Pathology and Pathologic Diagnosis of Radiation Lesions in the Gastro-Intestinal Tract. Am J Pathol. 1942 May;18(3):499–513. [PMC free article] [PubMed] [Google Scholar]

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