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. 1977 Aug;186(2):146–148. doi: 10.1097/00000658-197708000-00005

Mallory-Weiss syndrome. A changing clinical picture.

G J Todd, B A Zikria
PMCID: PMC1396703  PMID: 302109

Abstract

A retrospective study of 18 episodes of upper gastrointestinal (UGI) bleeding secondary to Mallory-Weiss syndrome occuring in 16 patients is presented. Reported cases published since 1969 have been summarized and compared with earlier collected series. It is evident that the clinical spectrum, prognosis, and opinion regarding etiology and treatment of the syndrome have changed in the last decade. Increased awareness of gastroesophageal lacerations secondary to emesis as well as other causes of significantly increased intraesophagogastric pressures, and widespread utilization of fiberoptic endoscopy have resulted in identification of Mallory-Weiss syndrome with increasing frequency. Less severe lacerations which are healing with medical therapy are being recognized. It is recommended that endoscopy by performed in all cases of UGI hemorrhage and that patients with Mallory-Weiss syndrome be managed medically unless hemorrhage is massive or persistent since nearly three of four patients can be successfully treated without operation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ATKINSON M., BOTTRILL M. B., EDWARDS A. T., MITCHELL W. M., PEET B. G., WILLIAMS R. E. Mucosal tears at the oesophagogastric junction (the Mallory-Weiss syndrome). Gut. 1961 Mar;2:1–11. doi: 10.1136/gut.2.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. DOBBINS W. O., 3rd Mallory-Weiss syndrome: a commonly overlooked cause of upper gastrointestinal bleeding. Report of three cases and review of the literature. Gastroenterology. 1963 May;44:689–695. [PubMed] [Google Scholar]
  3. Dill J. E., Wells R. F. Use of vasopressin in the Mallory-Weiss syndrome. N Engl J Med. 1971 Apr 15;284(15):852–853. doi: 10.1056/nejm197104152841516. [DOI] [PubMed] [Google Scholar]
  4. GOODMAN J. M. MALLORY-WEISS SYNDROME AND HYPOFIBRINOGENEMIA. COMPLICATION DURING SURGERY. JAMA. 1964 Oct 5;190:72–73. doi: 10.1001/jama.1964.03070140078022. [DOI] [PubMed] [Google Scholar]
  5. HARDY J. T. Mallory-Weiss syndrome; report of case diagnosed by gastroscopy. Gastroenterology. 1956 Apr;30(4):681–685. [PubMed] [Google Scholar]
  6. Holmes K. D. Mallory-Weiss syndrome: review of 20 cases and literature review. Ann Surg. 1966 Nov;164(5):810–820. doi: 10.1097/00000658-196611000-00004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Lundberg G. D., Mattei I. R., Davis C. J., Nelson D. E. Hemorrhage from gastroesophageal lacerations following closed-chest cardiac massage. JAMA. 1967 Oct 16;202(3):195–198. [PubMed] [Google Scholar]
  8. Miller A. C., Jr, Hirschowitz B. I. Twenty-three patients with Mallory-Weiss syndrome. South Med J. 1970 Apr;63(4):441–444. doi: 10.1097/00007611-197004000-00024. [DOI] [PubMed] [Google Scholar]
  9. Nielsen P. E., Zachariae F. The Mallory-Weiss syndrome. Acta Pathol Microbiol Scand Suppl. 1970;212(Suppl):166+–166+. [PubMed] [Google Scholar]
  10. Pagel J., Lindkear-Jensen S., Nielsen O. V. The Mallory-Weiss syndrome. Acta Chir Scand. 1975;141(6):532–535. [PubMed] [Google Scholar]
  11. Podgorny G., Linder J. H. Mallory-Weiss Syndrome reviewed. Int Surg. 1971 Feb;55(2):123–126. [PubMed] [Google Scholar]
  12. Saylor J. L., Tedesco F. J. Mallory-Weiss syndrome in perspective. Am J Dig Dis. 1975 Dec;20(12):1131–1134. doi: 10.1007/BF01070756. [DOI] [PubMed] [Google Scholar]
  13. Sparberg M. Roentgenographic documentation of the Mallory-Weiss syndrome. JAMA. 1968 Jan 8;203(2):151–152. [PubMed] [Google Scholar]
  14. St John D. J., Masterton J. P., Yeomans N. D., Dudley H. A. The Mallory-Weiss syndrome. Br Med J. 1974 Jan 26;1(5899):140–143. doi: 10.1136/bmj.1.5899.140. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Watts H. D., Admirand W. H. Mallory-Weiss syndrome. A reappraisal. JAMA. 1974 Dec 23;230(12):1674–1675. [PubMed] [Google Scholar]
  16. Weaver D. H., Maxwell J. G., Castleton K. B. Mallory-Weiss syndrome. Am J Surg. 1969 Dec;118(6):887–892. doi: 10.1016/0002-9610(69)90252-9. [DOI] [PubMed] [Google Scholar]
  17. Wells R. F. A common cause of upper gastrointestinal bleeding--the Mallory-Weiss syndrome. South Med J. 1967 Nov;60(11):1197–1201. doi: 10.1097/00007611-196711000-00013. [DOI] [PubMed] [Google Scholar]
  18. Wychulis A. R., Sasso A. Mallory-Weiss syndrome. Arch Surg. 1973 Dec;107(6):868–871. doi: 10.1001/archsurg.1973.01350240038011. [DOI] [PubMed] [Google Scholar]
  19. ZIKRIA B. A., ROSENTHAL A. D., POTTER R. T., FERRER J. M., Jr MALLORY-WEISS SYNDROME AND EMETOGENIC (SPONTANEOUS) RUPTURE OF THE ESOPHAGUS. Ann Surg. 1965 Jul;162:151–155. doi: 10.1097/00000658-196507000-00022. [DOI] [PMC free article] [PubMed] [Google Scholar]

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