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. 1990 Apr;80(4):428–430. doi: 10.2105/ajph.80.4.428

Recovery of hepatitis A virus from a water supply responsible for a common source outbreak of hepatitis A.

A B Bloch 1, S L Stramer 1, J D Smith 1, H S Margolis 1, H A Fields 1, T W McKinley 1, C P Gerba 1, J E Maynard 1, R K Sikes 1
PMCID: PMC1404566  PMID: 2156462

Abstract

An outbreak of hepatitis A occurred in a north Georgia trailer park served by a private well. Of 18 residents who were serosusceptible to hepatitis A virus (HAV), 16 (89%) developed hepatitis A. Well water samples were collected 3 months after illness onset in the index case and 28 days after illness onset in the last trailer park resident. Hepatitis A virus antigen (HAVAg) was detected in the samples by enzyme immunoassay from three of the five cell lines following two 30-day passages and from a fourth cell line following a third passage of 21 days.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Batik O., Craun G. F., Tuthill R. W., Kraemer D. F. An epidemiologic study of the relationship between hepatitis A and water supply characteristics and treatment. Am J Public Health. 1980 Feb;70(2):167–168. doi: 10.2105/ajph.70.2.167. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bowen G. S., McCarthy M. A. Hepatitis A associated with a hardware store water fountain and a contaminated well in Lancaster County, Pennsylvania, 1980. Am J Epidemiol. 1983 Jun;117(6):695–705. doi: 10.1093/oxfordjournals.aje.a113603. [DOI] [PubMed] [Google Scholar]
  3. Bryan J. A., Lehmann J. D., Setiady I. F., Hatch M. H. An outbreak of hepatitis-A associated with recreational lake water. Am J Epidemiol. 1974 Feb;99(2):145–154. doi: 10.1093/oxfordjournals.aje.a121595. [DOI] [PubMed] [Google Scholar]
  4. Carl M., Francis D. P., Maynard J. E. Food-borne hepatitis A: recommendations for control. J Infect Dis. 1983 Dec;148(6):1133–1135. doi: 10.1093/infdis/148.6.1133. [DOI] [PubMed] [Google Scholar]
  5. Dienstag J. L., Routenberg J. A., Purcell R. H., Hooper R. R., Harrison W. O. Foodhandler-associated outbreak of hepatitis type A. An immune electron microscopic study. Ann Intern Med. 1975 Nov;83(5):647–650. doi: 10.7326/0003-4819-83-5-647. [DOI] [PubMed] [Google Scholar]
  6. Katzenelson E., Fattal B., Hostovesky T. Organic flocculation: an efficient second-step concentration method for the detection of viruses in tap water. Appl Environ Microbiol. 1976 Oct;32(4):638–639. doi: 10.1128/aem.32.4.638-639.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Lemon S. M., Binn L. N., Marchwicki R. H. Radioimmunofocus assay for quantitation of hepatitis A virus in cell cultures. J Clin Microbiol. 1983 May;17(5):834–839. doi: 10.1128/jcm.17.5.834-839.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Lemon S. M. Type A viral hepatitis. New developments in an old disease. N Engl J Med. 1985 Oct 24;313(17):1059–1067. doi: 10.1056/NEJM198510243131706. [DOI] [PubMed] [Google Scholar]
  9. Sobsey M. D., Oglesbee S. E., Wait D. A. Evaluation of methods for concentrating hepatitis A virus from drinking water. Appl Environ Microbiol. 1985 Dec;50(6):1457–1463. doi: 10.1128/aem.50.6.1457-1463.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Wheeler C. M., Fields H. A., Schable C. A., Meinke W. J., Maynard J. E. Adsorption, purification, and growth characteristics of hepatitis A virus strain HAS-15 propagated in fetal rhesus monkey kidney cells. J Clin Microbiol. 1986 Mar;23(3):434–440. doi: 10.1128/jcm.23.3.434-440.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Wheeler C. M., Robertson B. H., Van Nest G., Dina D., Bradley D. W., Fields H. A. Structure of the hepatitis A virion: peptide mapping of the capsid region. J Virol. 1986 May;58(2):307–313. doi: 10.1128/jvi.58.2.307-313.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]

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