Abstract
Among a cohort of children in a poor urban setting in Brazil, the relative risk for the occurrence of a new episode of diarrhea in the two weeks following antibiotic use vs all other weeks was 1.44 (95% confidence interval (CI) = 1.33, 2.45). Among children ever [corrected] exposed to antibiotics, the odds ratio was 1.34 (95% CI = 0.84, 2.16) after stratifying by individual child and controlling for previous diarrhea. Further research is needed to confirm whether antibiotics are a risk factor for diarrhea in such settings.
Full text
PDF

Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Farrar W. E. Antibiotic resistance in developing countries. J Infect Dis. 1985 Dec;152(6):1103–1106. doi: 10.1093/infdis/152.6.1103. [DOI] [PubMed] [Google Scholar]
- Kunin C. M., Lipton H. L., Tupasi T., Sacks T., Scheckler W. E., Jivani A., Goic A., Martin R. R., Guerrant R. L., Thamlikitkul V. Social, behavioral, and practical factors affecting antibiotic use worldwide: report of Task Force 4. Rev Infect Dis. 1987 May-Jun;9 (Suppl 3):S270–S285. doi: 10.1093/clinids/9.supplement_3.s270. [DOI] [PubMed] [Google Scholar]
- Lusk R. H., Fekety F. R., Jr, Silva J., Jr, Bodendorfer T., Devine B. J., Kawanishi H., Korff L., Nakauchi D., Rogers S., Siskin S. B. Gastrointestinal side effects of clindamycin and ampicillin therapy. J Infect Dis. 1977 Mar;135 (Suppl):S111–S119. doi: 10.1093/infdis/135.supplement.s111. [DOI] [PubMed] [Google Scholar]
- Riley L. W., Cohen M. L., Seals J. E., Blaser M. J., Birkness K. A., Hargrett N. T., Martin S. M., Feldman R. A. Importance of host factors in human salmonellosis caused by multiresistant strains of Salmonella. J Infect Dis. 1984 Jun;149(6):878–883. doi: 10.1093/infdis/149.6.878. [DOI] [PubMed] [Google Scholar]
- Ryan C. A., Nickels M. K., Hargrett-Bean N. T., Potter M. E., Endo T., Mayer L., Langkop C. W., Gibson C., McDonald R. C., Kenney R. T. Massive outbreak of antimicrobial-resistant salmonellosis traced to pasteurized milk. JAMA. 1987 Dec 11;258(22):3269–3274. [PubMed] [Google Scholar]
- Schorling J. B., Wanke C. A., Schorling S. K., McAuliffe J. F., de Souza M. A., Guerrant R. L. A prospective study of persistent diarrhea among children in an urban Brazilian slum. Patterns of occurrence and etiologic agents. Am J Epidemiol. 1990 Jul;132(1):144–156. doi: 10.1093/oxfordjournals.aje.a115626. [DOI] [PubMed] [Google Scholar]
