Skip to main content
Immunology logoLink to Immunology
. 1972 Mar;22(3):423–430.

The specific immunoglobulin in hydatid disease

R M Matossian, G J Kane, S M Chantler, I Batty, H Sarhadian
PMCID: PMC1407791  PMID: 4554745

Abstract

The variation in the serum level of specific IgG, IgM and IgA antibodies during different stages of hydatid disease has been demonstrated by a technique of fluorescent microscopy that uses monospecific anti-human immunoglobulin conjugates and freeze-dried antigens. The technique is easy to perform and our results suggest that the test is sensitive and specific. Specific IgG antibodies are present in patients with either current or past infections. IgM antibodies, detected during periods of antigenic activity, disappear soon after removal of the cyst. In many cases IgA antibodies also disappear soon after removal of the cyst. Cross-reactions between the antigens and antibodies of hydatid disease and schistosomiasis are shown to be present mainly in the IgG immunoglobulin and only to a much smaller extent in the IgA.

Full text

PDF

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baublis J. V., Brown G. C. Specific response of the immunoglobulins to rubella infection. Proc Soc Exp Biol Med. 1968 May;128(1):206–210. doi: 10.3181/00379727-128-32979. [DOI] [PubMed] [Google Scholar]
  2. Brown G. C., Baublis J. V., O'Leary T. P. Development and duration of mumps fluorescent antibodies in various immunoglobulin fractions of human serum. J Immunol. 1970 Jan;104(1):86–94. [PubMed] [Google Scholar]
  3. Cherubin C. E. Nonspecific reactions to casoni antigen. Am J Trop Med Hyg. 1969 May;18(3):387–390. doi: 10.4269/ajtmh.1969.18.387. [DOI] [PubMed] [Google Scholar]
  4. DEUTSCH H. F., MORTON J. I. Dissociation of human serum macroglobulins. Science. 1957 Mar 29;125(3248):600–601. doi: 10.1126/science.125.3248.600. [DOI] [PubMed] [Google Scholar]
  5. FEINBERG J. G. Identification, discrimination and quantification in Ouchterlony gel plates. Int Arch Allergy Appl Immunol. 1957;11(3-4):129–152. [PubMed] [Google Scholar]
  6. FIREMAN P., VANNIER W. E., GOODMAN H. C. IMMUNOCHEMICAL STUDIES OF HUMAN SERUM FRACTIONATED BY GEL FILTRATION WITH SEPHADEX G-200. Proc Soc Exp Biol Med. 1964 Apr;115:845–849. doi: 10.3181/00379727-115-29054. [DOI] [PubMed] [Google Scholar]
  7. GARABEDIAN G. A., MATOSSIAN R. M., DJANIAN A. Y. An indirect hemagglutination test for hydatid disease. J Immunol. 1957 Apr;78(4):269–272. [PubMed] [Google Scholar]
  8. Gear J. H., Wolstenholme B. Bilharzia in South Africa with special reference to the laboratory diagnosis. S Afr Med J. 1966 Oct 8;40(36):877–880. [PubMed] [Google Scholar]
  9. Haire M., Hadden D. S. Immunoglobulin responses in rubella and its complications. Br Med J. 1970 Jul 18;3(5715):130–132. doi: 10.1136/bmj.3.5715.130. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Julian A. J., Logan L. C., Norins L. C. Early syphilis: immunoglobulins reactive in immunofluorescence and other serologic tests. J Immunol. 1969 May;102(5):1250–1259. [PubMed] [Google Scholar]
  11. Kagan I. G. A review of serological tests for the diagnosis of hydatid disease. Bull World Health Organ. 1968;39(1):25–37. [PMC free article] [PubMed] [Google Scholar]
  12. Kagan I. G., Maddison S. E., Norman L. Reactivity of human immunoglobulins in echinococcosis and trichinosis. Am J Trop Med Hyg. 1968 Jan;17(1):79–85. doi: 10.4269/ajtmh.1968.17.79. [DOI] [PubMed] [Google Scholar]
  13. Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
  14. Moriarty K. M. Antibodies in hydatid disease. J Lab Clin Med. 1968 Nov;72(5):721–730. [PubMed] [Google Scholar]

Articles from Immunology are provided here courtesy of British Society for Immunology

RESOURCES