Abstract
IgG heavy chain sub-classes were assayed in thirteen mixed cryoglobulins. In eight the distribution of sub-classes in the cryoglobulin was different from that in the serum. In two the IgG component of the cryoglobulin consisted entirely of IgG3. A restricted distribution of heavy chain sub-classes in mixed cryoglobulins probably reflects the heavy chain specificities of the antiglobulin components.
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Selected References
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