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. 1971 Dec;21(6):983–987.

Studies on the secretory immunological system of fowl

II. Immunoglobulin-producing cells associated with mucous membranes

G A Leslie, R B Crandall, Catherine A Crandall
PMCID: PMC1408259  PMID: 4943150

Abstract

Tissue sections from various areas of the digestive and respiratory tracts and spleens of chickens were examined by the fluorescent antibody technique for the presence of immunoglobulin-containing cells. All tissues examined contained lymphoid cells staining for immunoglobulin with the duodenum and caecal tonsils containing the highest concentrations of such cells. Spleens had approximately equal numbers of IgM- and IgY-containing cells; other tissues showed a predominance of IgY-containing cells.

The distribution of IgY-containing cells in the chicken gastrointestinal tract was similar to that generally associated with the secretory immunologic system of mammals which shows a preponderance of IgA-containing cells. These results in conjunction with other available data suggest that the chicken has evolved a secretory immunological system wherein the predominant serum immunoglobulin and the secretory immunoglobulin belong to the same class.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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