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. 1967 Mar;12(3):259–266.

The effect of 7S and 19S antibodies on the primary response to Salmonella typhi antigen

C W Fink, J J LoSpalluto
PMCID: PMC1409116  PMID: 6020396

Abstract

The effect of IgM and IgG antibodies on the primary response to Salmonella typhi antigen has been studied. IgG antibodies given before antigenic challenge or combined with antigen in antibody excess profoundly suppressed the formation of agglutinins in rabbits and humans. IgM antibodies appeared to have little or no inhibitory effect when given as complexes in antibody excess or when infused in relatively small amounts. Larger amounts do inhibit agglutinin formation in rabbits. It is suggested that the antibodies exert their inhibitory effect by combining with antigen and removing it as a stimulant for antibody formation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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