Abstract
Rank correlation analysis of serum IgG, IgA and IgM values from a large group of subjects showed that in health the amount of one class of immunoglobulin present in an individual is largely independent of the amounts of the other classes. A similar analysis of several sets of data from the literature concerning immunoglobulin levels in disease showed that even with severe disturbances of the immunoglobulin system, the levels remained independent.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Hahon N., Cooke K. O. Assay of Coxiella burnetii by enumeration of immunofluorescent infected cells. J Immunol. 1966 Oct;97(4):492–497. doi: 10.21236/ad0482256. [DOI] [PubMed] [Google Scholar]
- Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
- McKelvey E. M., Fahey J. L. Immunoglobulin changes in disease: quantitation on the basis of heavy polypeptide chains, IgG (gammaG), IgA (gammaA), and IgM (gammaM), and of light polypeptide chains, type K (I) and type L (II). J Clin Invest. 1965 Nov;44(11):1778–1787. doi: 10.1172/JCI105285. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WEST C. D., HINRICHS V., HINKLE N. H. Quantitative determination of the serum globulins beta-2A and beta-2M by immunoelectrophoretic analysis. J Lab Clin Med. 1961 Jul;58:137–148. [PubMed] [Google Scholar]