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. 1968 Jan;14(1):107–113.

Mode of action of anti-lymphocyte globulin

I. The distribution of rabbit anti-lymphocyte globulin injected into rats and mice

A M Denman, E P Frenkel
PMCID: PMC1409263  PMID: 4169721

Abstract

The distribution of rabbit anti-lymphocyte globulin (IgG) following injection into rats and mice has been studied by immunofluorescence and 131I labelling, and the tissues from treated animals have been examined by electron-microscopy. The results suggest that the anti-lymphocyte globulin reacts primarily with circulating lymphocytes, and that it penetrates the thymus, spleen and lymph nodes to a limited extent. These findings may explain the selective immuno-suppressive action of anti-lymphocyte globulin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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