Abstract
Horse anti-dog lymphocyte serum was found to suppress the immune response of dogs normally resulting from the injection of Salmonella typhi vaccine. Normal antibody levels of the dogs against Shigella dysenteriae were unaffected, however, by the anti-lymphocyte serum. The results suggest, therefore, that the natural antibodies may arise by a population of cells or by mechanisms different from those which produce antibodies as a result of deliberate antigenic stimulation.
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Selected References
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