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. 1968 Mar;14(3):347–356.

Studies on phagocytosis

III. Antigen clearance studies in invertebrates and poikilothermic vertebrates

Ann E Nelstrop, G Taylor, P Collard
PMCID: PMC1409342  PMID: 5638579

Abstract

The clearance of a secondary dose of T1 bacteriophage from the circulation of the goldfish, lamprey and shore crab has been shown to be more rapid than the clearance of a primary dose of phage. The phenomenon occurs in the absence of any detectable humoral antibody and appears similar to that previously described in rabbits.

The effect could not be demonstrated in the dogfish or land snail and it appears possible that some form of immunological paralysis or blockade occurred in these animals.

The results suggest that a phylogenetically more primitive immune response than the production of humoral antibody may exist in the animal kingdom.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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