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. 1968 Oct;15(4):571–580.

The use of subcellular fractions to raise anti-lymphocytic serum

E M Lance, P J Ford, M Ruszkiewicz
PMCID: PMC1409504  PMID: 4880132

Abstract

Subcellular preparations of mouse thymocytes were compared with respect to their power to raise in rabbits antisera which prolonged the survival of skin homografts. Of the fractions studied thymocyte `membrane' gave the most consistently good results, whereas thymocyte `mitochondria' gave rise to sera which were toxic in high dose. Whole mouse liver homogenate or liver subcellular fractions did not elicit potent antisera. It is concluded that thymocyte `membrane' best fulfils the requirements for an ideal material for immunization thus far studied and provides a convenient starting point for further purification.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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