MICROBIOLOGY. For the article “The total influenza vaccine failure of 1947 revisited: Major intrasubtypic antigenic change can explain failure of vaccine in a post-World War II epidemic,” by Edwin D. Kilbourne, Catherine Smith, Ian Brett, Barbara A. Pokorny, Bert Johansson, and Nancy Cox, which appeared in number 16, August 6, 2002, of Proc. Natl. Acad. Sci. USA (99, 10748–10752; First Published July 22, 2002; 10.1073/ pnas.162366899), in Table 7, three entries in the first two data columns appeared incorrectly. The corrected table appears below. The sequences submitted to GenBank are correct. In addition, on page 10751, left column, line 5, “7 of 11 antigenic sites” should read “8 of 11 antigenic sites.” These errors do not affect the interpretations and conclusions of the paper.
Table 7.
Antigenic site changes in the HA gene
Antigenic site
|
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sa
|
Sb
|
Ca1
|
Ca2
|
Cb
|
|||||||||
163 | 165 | 166 | 129 | 192 | 196 | 197 | 173 | 273 | 145 | 225 | 78 | 81 | |
1943–1947 | |||||||||||||
Weiss/43 | Y | R | N | Q | Q | A | S | R | D | L | E | ||
Marton/43 | N | N | N | Q | Q | G | S | S | G | Q | E | ||
FM/1/47 | K | S | K | K | R | E | P | S | G | L | K | ||
Rhodes/47 | N | S | K | R | R | E | S | S | G | L | K | ||
1977–1986 | |||||||||||||
USSR/90/77 | K | K | R | T | G | ||||||||
India/6263/80 | K | K | R | T | D | ||||||||
Chile/1/83 | K | K | R | T | N | ||||||||
Taiwan/1/86 | N | R | H | A | G |