*Note: As a result of the experimental study of certain chlorine antiseptics in localized peritoneal infections in dogs,1 the antiseptic post-operative treatment of cases of acute appendicitis requiring drainage was undertaken first in February, 1918, as a routine in the wards of the Surgical Service at the Presbyterian Hospital, New York City. Aside from the eighteen cases which have been treated by the writer, the method has been employed by others in thirteen cases of appendicitis and in a number of intra-abdominal drainage tracts accompanying other conditions.2 That a fair críterion might be established by which judgment could be passed upon the results attained by the antiseptic method, an analysis of 263 similar cases occurring during the past four years has been made. This period corresponds with that of the follow-up system of the hospital, and is, therefore, especially satisfactory in determining the incidence of certain sequelæ and late secondary procedures.
1 A Study of the Intra-abdominal Use of Dakin's Fluid and Dichloramine-T Solutions, with Special Reference to Local Peritoneal Infections. Jour. Exp. Med.
2 The Clinical Application of the Carrel-Dakin Method to Cases of Acute Appendicitis Requiring Drainage. Surg., Gynec. and Obst.