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. 1975 Apr;16(4):323–329. doi: 10.1136/gut.16.4.323

Absorption and secretion by the colon.

J H Cummings
PMCID: PMC1410924  PMID: 1093953

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aoyagi T., Engstrom G. W., Evans W. B., Summerskill W. H. Gastrointestinal urease in man. I. Activity of mucosal urease. Gut. 1966 Dec;7(6):631–635. doi: 10.1136/gut.7.6.631. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Archampong E. Q., Harris J., Clark C. G. The absorption and secretion of water and electrolytes across the healthy and the diseased human colonic mucosa measured in vitro. Gut. 1972 Nov;13(11):880–886. doi: 10.1136/gut.13.11.880. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BARRY R. J., SMYTH D. H. Transfer of short-chain fatty acids by the intestine. J Physiol. 1960 Jun;152:48–66. doi: 10.1113/jphysiol.1960.sp006468. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Banwell J. G., Gorbach S. L., Pierce N. F., Mitra R., Mondal A. Acute undifferentiated human diarrhea in the tropics. II. Alterations in intestinal fluid and electrolyte movements. J Clin Invest. 1971 Apr;50(4):890–900. doi: 10.1172/JCI106561. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Banwell J. G., Pierce N. F., Mitra R. C., Brigham K. L., Caranasos G. J., Keimowitz R. I., Fedson D. S., Thomas J., Gorbach S. L., Sack R. B. Intestinal fluid and electrolyte transport in human cholera. J Clin Invest. 1970 Jan;49(1):183–195. doi: 10.1172/JCI106217. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Bieberdorf F. A., Gorden P., Fordtran J. S. Pathogenesis of congenital alkalosis with diarrhea. Implications for the physiology of normal ileal electrolyte absorption and secretion. J Clin Invest. 1972 Aug;51(8):1958–1968. doi: 10.1172/JCI107002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Billich C. O., Levitan R. Effects of sodium concentration and osmolality on water and electrolyte absorption form the intact human colon. J Clin Invest. 1969 Jul;48(7):1336–1347. doi: 10.1172/JCI106100. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Bown R. L., Sladen G. E., Clark M. L., Dawson A. M. The production and transport of ammonia in the human colon. Gut. 1971 Oct;12(10):863–863. [PubMed] [Google Scholar]
  9. Bown R. L., Sladen G. E., Rousseau B., Gibson J. A., Clark M. L., Dawson A. M. A study of water and electrolyte transport by the excluded human colon. Clin Sci. 1972 Dec;43(6):891–902. doi: 10.1042/cs0430891. [DOI] [PubMed] [Google Scholar]
  10. Bustos Fernández L., Gonzalez E., Marzi A., Ledesma de Paolo M. I. Fecal acidorrhea. N Engl J Med. 1971 Feb 11;284(6):295–298. doi: 10.1056/NEJM197102112840603. [DOI] [PubMed] [Google Scholar]
  11. CLARKSON T. W., ROTHSTEIN A., CROSS A. Transport of monovalent anions by isolated small intestine of the rat. Am J Physiol. 1961 Apr;200:781–788. doi: 10.1152/ajplegacy.1961.200.4.781. [DOI] [PubMed] [Google Scholar]
  12. Carter M. J., Parsons D. S. Carbonic anhydrase activity of mucosa of small intestine and colon. Nature. 1968 Jul 13;219(5150):176–177. doi: 10.1038/219176a0. [DOI] [PubMed] [Google Scholar]
  13. Castell D. O., Moore E. W. Ammonia absorption from the human colon. The role of nonionic diffusion. Gastroenterology. 1971 Jan;60(1):33–42. [PubMed] [Google Scholar]
  14. Charron R. C., Leme C. E., Wilson D. R., Ing T. S., Wrong O. M. The effect of adrenal steroids on stool composition, as revealed by in vivo dialysis of faeces. Clin Sci. 1969 Aug;37(1):151–167. [PubMed] [Google Scholar]
  15. Cummings J. H., James W. P., Wiggins H. S. Role of the colon in ileal-resection diarrhoea. Lancet. 1973 Feb 17;1(7799):344–347. doi: 10.1016/s0140-6736(73)90131-1. [DOI] [PubMed] [Google Scholar]
  16. Cummings J. H., Milton-Thompson G. J., Billings J., Newman A., Misiewicz J. J. Proceedings: Studies on the site of production of diarrhoea induced by prostaglandins. Clin Sci Mol Med. 1974 Feb;46(2):15P–15P. doi: 10.1042/cs046015pa. [DOI] [PubMed] [Google Scholar]
  17. DAWSON A. M., HOLDSWORTH C. D., WEBB J. ABSORPTION OF SHORT CHAIN FATTY ACIDS IN MAN. Proc Soc Exp Biol Med. 1964 Oct;117:97–100. doi: 10.3181/00379727-117-29505. [DOI] [PubMed] [Google Scholar]
  18. DUTHIE H. L., ATWELL J. D. THE ABSORPTION OF WATER, SODIUM, AND POTASSIUM IN THE LARGE INTESTINE WITH PARTICULAR REFERENCE TO THE EFFECTS OF VILLOUS PAPILLOMAS. Gut. 1963 Dec;4:373–377. doi: 10.1136/gut.4.4.373. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. DUTHIE H. L., WATTS J. M., DEDOMBAL F. T., GOLIGHER J. C. SERUM ELECTROLYTES AND COLONIC TRANSFER OF WATER AND ELECTROLYTES IN CHRONIC ULCERATIVE COLITIS. Gastroenterology. 1964 Nov;47:525–530. [PubMed] [Google Scholar]
  20. Davies N. T., Munday K. A., Parsons B. J. The effect of angiotensin on rat intestinal fluid transfer. J Endocrinol. 1970 Sep;48(1):39–46. doi: 10.1677/joe.0.0480039. [DOI] [PubMed] [Google Scholar]
  21. Devroede G. J., Phillips S. F., Code C. F., Lind J. F. Regional differences in rates of insorption of sodium and water from the human large intestine. Can J Physiol Pharmacol. 1971 Dec;49(12):1023–1029. doi: 10.1139/y71-145. [DOI] [PubMed] [Google Scholar]
  22. Devroede G. J., Phillips S. F. Conservation of sodium, chloride, and water by the human colon. Gastroenterology. 1969 Jan;56(1):101–109. [PubMed] [Google Scholar]
  23. Down P. F., Agostini L., Murison J., Wrong O. M. The interrelations of faecal ammonia, pH and bicarbonate: evidence of colonic absorption of ammonia by non-ionic diffusion. Clin Sci. 1972 Jul;43(1):101–114. doi: 10.1042/cs0430101. [DOI] [PubMed] [Google Scholar]
  24. Edmonds C. J. Absorption of sodium and water by human rectum measured by a dialysis method. Gut. 1971 May;12(5):356–362. doi: 10.1136/gut.12.5.356. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Edmonds C. J., Godfrey R. C. Measurement of electrical potentials of the human rectum and pelvic colon in normal and aldosterone-treated patients. Gut. 1970 Apr;11(4):330–337. doi: 10.1136/gut.11.4.330. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Edmonds C. J., Marriott J. C. The effect of aldosterone and adrenalectomy on the electrical potential difference of rat colon and on the transport of sodium, potassium, chloride and bicarbonate. J Endocrinol. 1967 Dec;39(4):517–531. doi: 10.1677/joe.0.0390517. [DOI] [PubMed] [Google Scholar]
  27. Edmonds C. J., Pilcher D. Electrical potential difference and sodium and potassium fluxes across rectal mucosa in ulcerative colitis. Gut. 1973 Oct;14(10):784–789. doi: 10.1136/gut.14.10.784. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Edmonds C. J., Richards P. Measurement of rectal electrical potential difference as an instant screening-test for hyperaldosteronism. Lancet. 1970 Sep 26;2(7674):624–627. doi: 10.1016/s0140-6736(70)91397-8. [DOI] [PubMed] [Google Scholar]
  29. Elmslie R. G., Mulholland A. T., Shields R. Blocking by spironolactone (SC 9420) of the action of aldosterone upon the intestinal transport of potassium, sodium, and water. Gut. 1966 Dec;7(6):697–699. doi: 10.1136/gut.7.6.697. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Evans W. B., Aoyagi T., Summerskill W. H. Gastrointestinal urease in man. II. Urea hydrolysis and ammonia absorption in upper and lower gut lumen and the effect of neomycin. Gut. 1966 Dec;7(6):635–639. doi: 10.1136/gut.7.6.635. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Fordtran J. S. Organic anions in fecal contents. N Engl J Med. 1971 Feb 11;284(6):329–330. doi: 10.1056/NEJM197102112840612. [DOI] [PubMed] [Google Scholar]
  32. Gazet J. C. The surgical significance of the ileo-caecal junction. Ann R Coll Surg Engl. 1968 Jul;43(1):19–38. [PMC free article] [PubMed] [Google Scholar]
  33. Gibson J. A., Sladen G. E., Dawson A. M. Proceedings: Studies in the role of the colon in urea metabolism. Gut. 1973 Oct;14(10):816–816. [PMC free article] [PubMed] [Google Scholar]
  34. Giller J., Phillips S. F. Electrolyte absorption and secretion in the human colon. Am J Dig Dis. 1972 Nov;17(11):1003–1011. doi: 10.1007/BF02239140. [DOI] [PubMed] [Google Scholar]
  35. Gingell J. C., Davies M. W., Shields R. Effect of a synthetic gastrin-like pentapeptide upon the intestinal transport of sodium, potassium, and water. Gut. 1968 Feb;9(1):111–116. doi: 10.1136/gut.9.1.111. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Gompertz D., Brooks A. P., Gaya H., Spiers A. S. Volatile fatty acids in the faeces of patients in 'germ-free' isolation. Gut. 1973 Mar;14(3):183–186. doi: 10.1136/gut.14.3.183. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Grady G. F., Duhamel R. C., Moore E. W. Active transport of sodium by human colon in vitro. Gastroenterology. 1970 Oct;59(4):583–588. [PubMed] [Google Scholar]
  38. Harris J., Shields R. Absorption and secretion of water and electrolytes by the intact human colon in diffuse untreated proctocolitis. Gut. 1970 Jan;11(1):27–33. doi: 10.1136/gut.11.1.27. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Head L. H., Heaton J. W., Jr, Kivel R. M. Absorption of water and electrolytes in Crohn's disease of the colon. Gastroenterology. 1969 Mar;56(3):571–579. [PubMed] [Google Scholar]
  40. Hornych A., Meyer P., Milliez P. Angiotensin, vasopressin, and cyclic AMP: effects on sodium and water fluxes in rat colon. Am J Physiol. 1973 May;224(5):1223–1229. doi: 10.1152/ajplegacy.1973.224.5.1223. [DOI] [PubMed] [Google Scholar]
  41. Johnson G. K., Soergel K. H., Hensley G. T., Dodds W. J., Hogan W. J. Cronkite-Canada syndrome: gastrointestinal pathophysiology and morphology. Gastroenterology. 1972 Jul;63(1):140–152. [PubMed] [Google Scholar]
  42. Jones E. A., Smallwood R. A., Craigie A., Rosenoer V. M. The enterohepatic circulation of urea nitrogen. Clin Sci. 1969 Dec;37(3):825–836. [PubMed] [Google Scholar]
  43. KANAGHINIS T., LUBRAN M., COGHILL N. F. THE COMPOSITION OF ILEOSTOMY FLUID. Gut. 1963 Dec;4:322–338. doi: 10.1136/gut.4.4.322. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. KURIAKI K., MAGEE D. F. ON THE CARBONIC ANHYDRASE ACTIVITY OF THE ALIMINTARY CANAL AND PANCREAS. Life Sci. 1964 Dec;3:1377–1382. doi: 10.1016/0024-3205(64)90077-3. [DOI] [PubMed] [Google Scholar]
  45. LEVITAN R., FORDTRAN J. S., BURROWS B. A., INGELFINGER F. J. Water and salt absorption in the human colon. J Clin Invest. 1962 Sep;41:1754–1759. doi: 10.1172/JCI104634. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. LEVITAN R., INGELFINGER F. J. EFFECT OF D-ALDOSTERONE ON SALT AND WATER ABSORPTION FROM THE INTACT HUMAN COLON. J Clin Invest. 1965 May;44:801–808. doi: 10.1172/JCI105192. [DOI] [PMC free article] [PubMed] [Google Scholar]
  47. Levitan R., Brudno S. Permeability of the rectosigmoid mucosa to tritiated water in normal subjects and in patients with milk idiopathic ulcerative colitis. Gut. 1967 Feb;8(1):15–19. doi: 10.1136/gut.8.1.15. [DOI] [PMC free article] [PubMed] [Google Scholar]
  48. Levitan R. Salt and water absorption from the normal human colon: effect of 9-alpha-fluorohydrocortisone administration. J Lab Clin Med. 1967 Apr;69(4):558–564. [PubMed] [Google Scholar]
  49. Maren T. H. Carbonic anhydrase: chemistry, physiology, and inhibition. Physiol Rev. 1967 Oct;47(4):595–781. doi: 10.1152/physrev.1967.47.4.595. [DOI] [PubMed] [Google Scholar]
  50. Matty A. J., Noble H. M. Hormones and water movement through the vertebrate intestine. Hormones. 1972;3(1):42–64. doi: 10.1159/000178257. [DOI] [PubMed] [Google Scholar]
  51. McBee R. H. Metabolic contributions of the cecal flora. Am J Clin Nutr. 1970 Nov;23(11):1514–1518. doi: 10.1093/ajcn/23.11.1514. [DOI] [PubMed] [Google Scholar]
  52. Mossberg S. M., Ross G. Ammonia movement in the small intestine: preferential transport by the ileum. J Clin Invest. 1967 Apr;46(4):490–498. doi: 10.1172/JCI105551. [DOI] [PMC free article] [PubMed] [Google Scholar]
  53. Parsons D. S. Salt and water absorption by the intestinal tract. Br Med Bull. 1967 Sep;23(3):252–257. doi: 10.1093/oxfordjournals.bmb.a070566. [DOI] [PubMed] [Google Scholar]
  54. Pearson A. J., Sladen G. E., Edmonds C. J., Tavill A. S., Wills M. R., McIntyre N. The pathophysiology of congenital chloridorrhoea. Q J Med. 1973 Jul;42(167):453–466. [PubMed] [Google Scholar]
  55. Phillips S. F. Absorption and secretion by the colon. Gastroenterology. 1969 May;56(5):966–971. [PubMed] [Google Scholar]
  56. Phillips S. F., Giller J. The contribution of the colon to electrolyte and water conservation in man. J Lab Clin Med. 1973 May;81(5):733–746. [PubMed] [Google Scholar]
  57. Picou D., Phillips M. Urea metabolism in malnourished and recovered children receiving a high or low protein diet. Am J Clin Nutr. 1972 Nov;25(11):1261–1266. doi: 10.1093/ajcn/25.11.1261. [DOI] [PubMed] [Google Scholar]
  58. Powell D. W., Malawer S. J. Relationship between water and solute transport from isosmotic solutions by rat intestine in vivo. Am J Physiol. 1968 Jul;215(1):49–55. doi: 10.1152/ajplegacy.1968.215.1.49. [DOI] [PubMed] [Google Scholar]
  59. Rask-Madsen J., Hammersgaard E. A., Knudsen E. Rectal electrolyte transport and mucosal permeability in ulcerative colitis and Crohn's disease. J Lab Clin Med. 1973 Mar;81(3):342–353. [PubMed] [Google Scholar]
  60. Rask-Madsen J. Simultaneous measurement of electrical polarization and electrolyte transport by the entire normal and inflamed human colon during in vivo perfusion. Scand J Gastroenterol. 1973;8(4):327–336. [PubMed] [Google Scholar]
  61. Richards P. Clinical investigation of the effects of adrenal corticosteroid excess on the colon. Lancet. 1969 Mar 1;1(7592):437–442. doi: 10.1016/s0140-6736(69)91480-9. [DOI] [PubMed] [Google Scholar]
  62. Richards P., Metcalfe-Gibson A., Ward E. E., Wrong O., Houghton B. J. Utilisation of ammonia nitrogen for protein synthesis in man, and the effect of protein restriction and uraemia. Lancet. 1967 Oct 21;2(7521):845–849. doi: 10.1016/s0140-6736(67)92588-3. [DOI] [PubMed] [Google Scholar]
  63. Richards P. Nutritional potential of nitrogen recycling in man. Am J Clin Nutr. 1972 Jun;25(6):615–625. doi: 10.1093/ajcn/25.6.615. [DOI] [PubMed] [Google Scholar]
  64. Rubinstein R., Howard A. V., Wrong O. M. In vivo dialysis of faeces as a method of stool analysis. IV. The organic anion component. Clin Sci. 1969 Oct;37(2):549–564. [PubMed] [Google Scholar]
  65. Sallee V. L., Dietschy J. M. Determinants of intestinal mucosal uptake of short- and medium-chain fatty acids and alcohols. J Lipid Res. 1973 Jul;14(4):475–484. [PubMed] [Google Scholar]
  66. Salter D. N. The influence of gut micro-organisms on utilization of dietary protein. Proc Nutr Soc. 1973 Sep;32(2):65–71. [PubMed] [Google Scholar]
  67. Shields R. Absorption and secretion of electrolytes and water by the human colon, with particular reference to benign adenoma and papilloma. Br J Surg. 1966 Oct;53(10):893–897. doi: 10.1002/bjs.1800531019. [DOI] [PubMed] [Google Scholar]
  68. Shields R., Miles J. B., Gilbertson C. Absorption and secretion of water and electrolytes by the intact colon in a patient with primary aldosteronism. Br Med J. 1968 Jan 13;1(5584):93–96. doi: 10.1136/bmj.1.5584.93. [DOI] [PMC free article] [PubMed] [Google Scholar]
  69. Shields R., Mulholland A. T., Elmslie R. G. Action of aldosterone upon the intestinal transport of potassium, sodium, and water. Gut. 1966 Dec;7(6):686–696. doi: 10.1136/gut.7.6.686. [DOI] [PMC free article] [PubMed] [Google Scholar]
  70. Southgate D. A., Durnin J. V. Calorie conversion factors. An experimental reassessment of the factors used in the calculation of the energy value of human diets. Br J Nutr. 1970 Jun;24(2):517–535. doi: 10.1079/bjn19700050. [DOI] [PubMed] [Google Scholar]
  71. Torres-Pinedo R., Lavastida M., Rivera C. L., Rodrïguez H., Ortiz A. Studies on infant diarrhea. I. A comparison of the effects of milk feeding and intravenous therapy upon the composition and volume of the stool and urine. J Clin Invest. 1966 Apr;45(4):469–480. doi: 10.1172/JCI105361. [DOI] [PMC free article] [PubMed] [Google Scholar]
  72. Turnberg L. A. Abnormalities in intestinal electrolyte transport in congenital chloridorrhoea. Gut. 1971 Jul;12(7):544–551. doi: 10.1136/gut.12.7.544. [DOI] [PMC free article] [PubMed] [Google Scholar]
  73. Turnberg L. A., Bieberdorf F. A., Morawski S. G., Fordtran J. S. Interrelationships of chloride, bicarbonate, sodium, and hydrogen transport in the human ileum. J Clin Invest. 1970 Mar;49(3):557–567. doi: 10.1172/JCI106266. [DOI] [PMC free article] [PubMed] [Google Scholar]
  74. Turnberg L. A. Electrolyte absorption from the colon. Gut. 1970 Dec;11(12):1049–1054. doi: 10.1136/gut.11.12.1049. [DOI] [PMC free article] [PubMed] [Google Scholar]
  75. WALSER M., BODENLOS L. J. Urea metabolism in man. J Clin Invest. 1959 Sep;38:1617–1626. doi: 10.1172/JCI103940. [DOI] [PMC free article] [PubMed] [Google Scholar]
  76. WRONG O., METCALFE-GIBSON A., MORRISON R. B., NG S. T., HOWARD A. V. IN VIVO DIALYSIS OF FAECES AS A METHOD OF STOOL ANALYSIS. I. TECHNIQUE AND RESULTS IN NORMAL SUBJECTS. Clin Sci. 1965 Apr;28:357–375. [PubMed] [Google Scholar]
  77. Wilson D. R., Ing T. S., Metcalfe-Gibson A., Wrong O. M. The chemical composition of faeces in uraemia, as revealed by in-vivo faecal dialysis. Clin Sci. 1968 Oct;35(2):197–209. [PubMed] [Google Scholar]
  78. Wingate D. L., Krag E., Mekhjian H. S., Phillips S. F. Relationships between ion and water movement in the human jejunum, ileum and colon during perfusion with bile acids. Clin Sci Mol Med. 1973 Nov;45(5):593–606. doi: 10.1042/cs0450593. [DOI] [PubMed] [Google Scholar]
  79. Wolpert E., Phillips S. F., Summerskill W. H. Transport of urea and ammonia production in the human colon. Lancet. 1971 Dec 25;2(7739):1387–1390. doi: 10.1016/s0140-6736(71)90667-2. [DOI] [PubMed] [Google Scholar]
  80. Wrong O. Aldosterone and electrolyte movements in the colon. Br Med J. 1968 Feb 10;1(5588):379–380. doi: 10.1136/bmj.1.5588.379-c. [DOI] [PMC free article] [PubMed] [Google Scholar]

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