Abstract
The clinical significance of sarcoid-like granulomata in recurrent Crohn's disease has been investigated in 90 patients. The recurrence rate for non-granulomatous disease was double that of granulomatous disease. In granulomatous disease, involvement of the mesenteric lymph nodes did not affect the recurrence rate. This suggests that sarcoid-like granulomata reflect the patients' immune response and support the view that excision of the lymphatic drainage en bloc with affected bowel is not indicated.
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Selected References
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- ANTONIUS J. I., GUMP F. E., LATTES R., LEPORE M. A study of certain microscopic features in regional enteritis, and their possible prognostic significance. Gastroenterology. 1960 Jun;38:889–905. [PubMed] [Google Scholar]
- De Dombal F. T., Burton I., Goligher J. C. Recurrence of Crohn's disease after primary excisional surgery. Gut. 1971 Jul;12(7):519–527. doi: 10.1136/gut.12.7.519. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LOCKHART-MUMMERY H. E., MORSON B. C. CROHN'S DISEASE OF THE LARGE INTESTINE. Gut. 1964 Dec;5:493–509. doi: 10.1136/gut.5.6.493. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Morson B. S. Histopathology of Crohn's disease. Proc R Soc Med. 1968 Jan;61(1):79–81. [PMC free article] [PubMed] [Google Scholar]
- WARREN S., SOMMERS S. C. Pathology of regional ileitis and ulcerative colitis. J Am Med Assoc. 1954 Jan 16;154(3):189–193. doi: 10.1001/jama.1954.02940370001001. [DOI] [PubMed] [Google Scholar]