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. 1976 May;17(5):328–331. doi: 10.1136/gut.17.5.328

T cell depletion in untreated adult coeliac disease.

D P O'Donoghue, M Lancaster-Smith, P Laviniere, P J Kumar
PMCID: PMC1411143  PMID: 1084314

Abstract

The proportional and absolute numbers of circulating thymus dependent lymphocytes (T cells) were reduced in untreated patients with coeliac disease but were normal after treatment with a gluten free diet. There was an inverse correlation between circulating T cell numbers and jejunal intraepithelial lymphocytes. This evidence suggests a possible role for T cells in the pathogenesis of coeliac disease and is a further example of disturbed cell mediated immunity in this condition.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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