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. 1977 Sep;18(9):709–712. doi: 10.1136/gut.18.9.709

Postprandial gastro-oesophageal reflux in healthy people.

M D Kaye
PMCID: PMC1411657  PMID: 23983

Abstract

Distal oesophageal pH was monitored for three hours after a standard meal in 10 young healthy subjects without symptoms of gastro-oesophageal reflux. Episodes of reflux occurred in nine of these subjects; and, in five, oesophageal pH was less than 5 for between 11 and 75% of the first postprandial hour. Intermittent incompetence of the lower oesophageal sphincter after food must, therefore, be regarded as a normal phenomenon. The method described would be suitable for the evaluation of agents believed to weaken or to strengthen the lower oesophageal sphincter.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Babka J. C., Hager G. W., Castell D. O. The effect of body position on lower esophageal sphincter pressure. Am J Dig Dis. 1973 May;18(5):441–442. doi: 10.1007/BF01071996. [DOI] [PubMed] [Google Scholar]
  2. Behar J., Biancani P. Effect of oral metoclopramide on gastroesophageal reflux in the post-cibal state. Gastroenterology. 1976 Mar;70(3):331–335. [PubMed] [Google Scholar]
  3. Behar J., Biancani P., Sheahan D. G. Evaluation of esophageal tests in the diagnosis of reflux esophagitis. Gastroenterology. 1976 Jul;71(1):9–15. [PubMed] [Google Scholar]
  4. Benz L. J., Hootkin L. A., Margulies S., Donner M. W., Cauthorne R. T., Hendrix T. R. A comparison of clinical measurements of gastroesophageal reflux. Gastroenterology. 1972 Jan;62(1):1–5. [PubMed] [Google Scholar]
  5. Boesby S. Gastro-oesophageal acid reflux and sphincter pressure in normal human subjects. Scand J Gastroenterol. 1975;10(7):731–736. [PubMed] [Google Scholar]
  6. Bombeck C. T., Helfrich G. B., Nyhus L. M. Planning surgery for reflux esophagitis and hiatus hernia. Surg Clin North Am. 1970 Feb;50(1):29–44. doi: 10.1016/s0039-6109(16)39029-6. [DOI] [PubMed] [Google Scholar]
  7. Haddad J. K. Relation of gastroesophageal reflux to yield sphincter pressures. Gastroenterology. 1970 Feb;58(2):175–184. [PubMed] [Google Scholar]
  8. Ismail-Beigi F., Horton P. F., Pope C. E., 2nd Histological consequences of gastroesophageal reflux in man. Gastroenterology. 1970 Feb;58(2):163–174. [PubMed] [Google Scholar]
  9. Johnson L. F., Demeester T. R. Twenty-four-hour pH monitoring of the distal esophagus. A quantitative measure of gastroesophageal reflux. Am J Gastroenterol. 1974 Oct;62(4):325–332. [PubMed] [Google Scholar]
  10. PICCONE V. A., GUTELIUS J. R., MCCORRISTON J. R. A MULTIPHASE ESOPHAGEAL PH TEST FOR GASTROESOPHAGEAL REFLUX. Surgery. 1965 May;57:638–646. [PubMed] [Google Scholar]
  11. Pattrick F. G. Investigation of gastroesophageal reflux in various positions with a two-lumen pH electrode. Gut. 1970 Aug;11(8):659–667. doi: 10.1136/gut.11.8.659. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Pope C. E. Editorial: Is LES enough? Gastroenterology. 1976 Aug;71(2):328–329. [PubMed] [Google Scholar]
  13. Skinner D. B., Booth D. J. Assessment of distal esophageal function in patients with hiatal hernia and-or gastroesophageal reflux. Ann Surg. 1970 Oct;172(4):627–637. doi: 10.1097/00000658-197010000-00009. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Spencer J. Prolonged pH recording in the study of gastro-oesophageal reflux. Br J Surg. 1969 Dec;56(12):912–914. doi: 10.1002/bjs.1800561211. [DOI] [PubMed] [Google Scholar]
  15. TUTTLE S. G., BETTARELLO A., GROSSMAN M. I. Esophageal acid perfusion test and a gastroesophageal reflux test in patients with esophagitis. Gastroenterology. 1960 Jun;38:861–872. [PubMed] [Google Scholar]
  16. TUTTLE S. G., GROSSMAN M. I. Detection of gastro-esophageal reflux by simultaneous measurement of intraluminal pressure and pH. Proc Soc Exp Biol Med. 1958 Jun;98(2):225–227. doi: 10.3181/00379727-98-23998. [DOI] [PubMed] [Google Scholar]
  17. Venkatachalam B., Da Costa L. R., Ip S. K., Beck I. T. What is a normal esophagogastric junction? Gastroenterology. 1972 Apr;62(4):521–527. [PubMed] [Google Scholar]

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