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. 1977 Oct;18(10):833–835. doi: 10.1136/gut.18.10.833

Effect of cigarette smoking on the lower oesophageal sphincter.

D K Chattopadhyay, M G Greaney, T T Irvin
PMCID: PMC1411683  PMID: 590842

Abstract

Observations on the effect of smoking on lower oesophageal sphincter pressure (LOSP) are based on station pull-through techniques of eosophageal manometry and recent studies have suggested that these techniques are inaccurate. Reproducible measurements of LOSP may be achieved with a rapid pull-through (RPT) method of manometry. This method was used to determine the effect of cigarette smoking on LOSP in 10 asymptomatic volunteers and in a group of 10 patients with symptoms of gastro-oesophageal reflux. Basal LOSP measurements in the two groups were not significantly different but LOSP was reduced by 19% in asymptomatic subjects (p less than 0-01) and by 21% in symptomatic patients (p less than 0-02) during cigarette smoking. The results suggest that smoking should be avoided in the clinical management of gastro-oesophageal reflux.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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