Skip to main content
Gut logoLink to Gut
. 1971 Aug;12(8):611–615. doi: 10.1136/gut.12.8.611

An evaluation of 113mindium DTPA chelate in the measurement of gastric emptying by scintiscanning

R C Heading, P Tothill, A J Laidlaw, D J C Shearman
PMCID: PMC1411749  PMID: 18668826

Abstract

The sequential scintiscanning technique was used to determine gastric emptying rates in adult human subjects after ingestion of a meal of cornflakes and milk to which a gamma-emitting radioactive isotope had been added.

Comparison of emptying rates using 113mIn DTPA chelate and 51Cr sodium chromate showed that significantly slower rates were recorded with chromate, and studies in vitro demonstrated adsorption of chromate to the solid component of the meal. The results imply that the liquid phase of the gastric contents after a meal is discharged through the pylorus more rapidly than the solid phase. Scintiscanning with indium chelate provides a measurement of the emptying of the liquid phase of the gastric contents.

Full text

PDF
611

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brömster D., Carlberger G., Lundh G. Measurement of gastric emptying rate using 131-I-HSA. A methodological study in man. Scand J Gastroenterol. 1968;3(6):641–653. [PubMed] [Google Scholar]
  2. Griffith G. H., Owen G. M., Kirkman S., Shields R. Measurement of rate of gastric emptying using chromium-51. Lancet. 1966 Jun 4;1(7449):1244–1245. doi: 10.1016/s0140-6736(66)90247-9. [DOI] [PubMed] [Google Scholar]
  3. HANSKY J., CONNELL A. M. Measurement of gastrointestinal transit using radioactive chromium. Gut. 1962 Jun;3:187–188. doi: 10.1136/gut.3.2.187. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. HUNT J. N., SPURRELL W. R. The pattern of emptying of the human stomach. J Physiol. 1951 Apr;113(2-3):157–168. doi: 10.1113/jphysiol.1951.sp004562. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Harvey R. F., Mackie D. B., Brown N. J., Keeling D. H., Davies W. T. Measurement of gastric emptying time with a gamma camera. Lancet. 1970 Jan 3;1(7636):16–18. doi: 10.1016/s0140-6736(70)90525-8. [DOI] [PubMed] [Google Scholar]
  6. Jones T., Clark J. C., Kocak N., Cox A. G., Glass H. I. Measurement of gastric emptying using the scintillation camera and 129Cs. Br J Radiol. 1970 Aug;43(512):537–541. doi: 10.1259/0007-1285-43-512-537. [DOI] [PubMed] [Google Scholar]
  7. THOMAS J. E. Mechanics and regulation of gastric emptying. Physiol Rev. 1957 Oct;37(4):453–474. doi: 10.1152/physrev.1957.37.4.453. [DOI] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES