Abstract
The gastritis associated with chronic gastric ulcer has been studied by means of biopsy specimens taken under vision through a fibreoptic gastroscope from four standard sites in the stomach. Observations have been made in patients with untreated gastric ulcer and also in patients after medical or surgical treatment of the ulcer. The gastritis is usually widespread in chronic peptic ulcer of the body of the stomach, whereas it is commonly more localized in chronic prepyloric ulcer. Superficial or atrophic gastritis has been found to persist or even worsen after healing of the ulcer, whether the treatment was medical or surgical. This finding suggests that gastritis is the basic disease process and that gastric ulceration is a secondary phenomenon.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Gear M. W., Truelove S. C., Williams D. G., Massarella G. R., Boddington M. M. Gastric cancer simulating benign gastric ulcer. Br J Surg. 1969 Oct;56(10):739–742. doi: 10.1002/bjs.1800561011. [DOI] [PubMed] [Google Scholar]
- HANCOCK P. E. T., SHINER M. Combined gastroscopy and gastric biopsy under direct vision. Lancet. 1958 Jun 7;1(7032):1204–1205. doi: 10.1016/s0140-6736(58)91909-3. [DOI] [PubMed] [Google Scholar]
- HEBBEL R. The topography of chronic gastritis in otherwise normal stomachs. Am J Pathol. 1949 Jan;25(1):125–141. [PMC free article] [PubMed] [Google Scholar]
- Hebbel R. Chronic Gastritis: Its Relation to Gastric and Duodenal Ulcer and to Gastric Carcinoma. Am J Pathol. 1943 Jan;19(1):43–71. [PMC free article] [PubMed] [Google Scholar]
- JOSKE R. A., FINCKH E. S., WOOD I. J. Gastric biopsy; a study of 1,000 consecutive successful gastric biopsies. Q J Med. 1955 Jul;24(95):269–294. [PubMed] [Google Scholar]
- MacDonald W. C., Rubin C. E. Gastric biopsy--a critical evaluation. Gastroenterology. 1967 Jul;53(1):143–170. [PubMed] [Google Scholar]
- PALMER E. D. Gastritis: a revaluation. Medicine (Baltimore) 1954 Sep;33(3):199–290. doi: 10.1097/00005792-195409000-00002. [DOI] [PubMed] [Google Scholar]
- Sanders G. B., Mecray P. M. PSEUDOGASTRITIS OF OPERATIVE ORIGIN. Ann Surg. 1941 Dec;114(6):986–996. doi: 10.1097/00000658-194112000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stemmermann G. N., Hayashi T. Intestinal metaplasia of the gastric mucosa: a gross and microscopic study of its distribution in various disease states. J Natl Cancer Inst. 1968 Sep;41(3):627–634. [PubMed] [Google Scholar]